C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000423725 NDUFS1-005 ENSG00000023228 9606 - 2:206123819-206159509 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyENST00000423725
Transcript ID Kidney
ENST00000423725 13.948±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039O CIL_00039O_0001 CGP 2:205993721-206159603
CIL_0001R4 CIL_0001R4_0001 CGP 2:206114817-206162928

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005743 TAS mitochondrial inner membrane
GO:0005747 IDA mitochondrial respiratory chain complex I
GO:0005758 IDA mitochondrial intermembrane space
GO:0006120 NAS mitochondrial electron transport, NADH to ubiquinone
GO:0008137 IEA:NAS NADH dehydrogenase (ubiquinone) activity
GO:0008637 IDA apoptotic mitochondrial changes
GO:0009055 NAS:IEA electron carrier activity
GO:0016020 IEA membrane
GO:0016491 IEA oxidoreductase activity
GO:0016651 IEA oxidoreductase activity, acting on NAD(P)H
GO:0022904 TAS respiratory electron transport chain
GO:0042773 IEA ATP synthesis coupled electron transport
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045333 IMP cellular respiration
GO:0046034 IMP ATP metabolic process
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051537 IEA 2 iron, 2 sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0072593 IMP reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168099 Ndufs1-006 protein_coding Mus_musculus 0 2726
ENSMUST00000027111 Ndufs1-001 protein_coding Mus_musculus 0 2726
ENSMUST00000185827 Ndufs1-005 retained_intron Mus_musculus 0 1375
ENSMUST00000140612 Ndufs1-002 retained_intron Mus_musculus 0 1194
ENSMUST00000185847 Ndufs1-011 protein_coding Mus_musculus 0 580
ENSMUST00000187835 Ndufs1-013 retained_intron Mus_musculus 0 390
ENSMUST00000187756 Ndufs1-012 nonsense_mediated_decay Mus_musculus 0 219
ENSMUST00000186569 Ndufs1-004 retained_intron Mus_musculus 1.4013e-45 189
ENSMUST00000190095 Ndufs1-003 retained_intron Mus_musculus 2e-29 135

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