C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: macrophage scavenger receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000038945 MSR1 9606 - 8:16107878-16567490 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262101 MSR1-001 16109431-16192715 protein_coding
  ENST00000350896 MSR1-201 16107878-16192791 protein_coding
  ENST00000355282 MSR1-002 16110085-16177988 protein_coding
  ENST00000381998 MSR1-003 16139319-16192659 protein_coding
  ENST00000445506 MSR1-004 16110046-16186272 protein_coding
  ENST00000517522 MSR1-013 16368086-16383328 processed_transcript
  ENST00000518026 MSR1-007 16175263-16567362 protein_coding
  ENST00000518343 MSR1-010 16256331-16567420 processed_transcript
  ENST00000518960 MSR1-008 16175210-16215074 protein_coding
  ENST00000519060 MSR1-005 16140655-16192651 nonsense_mediated_decay
  ENST00000520846 MSR1-012 16467752-16495880 processed_transcript
  ENST00000521876 MSR1-011 16250398-16511916 processed_transcript
  ENST00000522130 MSR1-009 16467764-16567490 processed_transcript
  ENST00000522672 MSR1-006 16120889-16164251 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262101ENST00000350896ENST00000355282ENST00000381998ENST00000445506ENST00000519060
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262101 N/A N/A 0.642±0.00 N/A 5.106±0.00 1.024±0.00 N/A N/A 1.456±0.00 N/A N/A N/A N/A N/A
ENST00000350896 3.197±0.00 N/A N/A 0.130±0.00 N/A N/A N/A 0.897±0.00 0.460±0.00 6.092±1.49 N/A N/A 1.698±0.00 N/A
ENST00000355282 N/A N/A 1.700±0.00 0.269±0.00 4.506±0.00 0.962±0.00 N/A 1.816±0.00 1.331±0.00 N/A N/A N/A N/A N/A
ENST00000381998 11.153±0.00 1.428±0.00 0.462±0.00 1.321±0.00 4.094±0.91 1.152±0.00 0.870±0.19 1.974±0.00 1.389±0.81 20.131±6.34 0.286±0.00 2.049±0.47 3.575±0.85 0.856±0.38
ENST00000445506 N/A N/A N/A 0.931±0.00 N/A N/A 0.639±0.00 1.379±0.00 N/A 16.802±0.00 0.367±0.00 2.119±0.00 N/A N/A
ENST00000519060 9.156±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000456 CIL_000456_0001 CGP 8:15417215-16567490
CIL_0001VY CIL_0001VY_0001 CGP 8:16107878-17002181

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005581 IEA collagen trimer
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006898 IEA receptor-mediated endocytosis
GO:0007165 IEA signal transduction
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0010886 ISS positive regulation of cholesterol storage
GO:0016020 IEA membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 ISS cholesterol transport
GO:0030666 TAS endocytic vesicle membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0034362 IEA low-density lipoprotein particle
GO:0034381 ISS plasma lipoprotein particle clearance
GO:0042953 IEA lipoprotein transport
GO:0071407 IEA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000025044 Msr1 macrophage scavenger receptor 1 protein_coding Mus_musculus

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