C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: macrophage scavenger receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000445506 MSR1-004 ENSG00000038945 9606 - 8:16110046-16186272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLungMuscleOvaryENST00000445506
Transcript ID Brain Heart Kidney Lung Muscle Ovary
ENST00000445506 0.931±0.00 0.639±0.00 1.379±0.00 16.802±0.00 0.367±0.00 2.119±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000456 CIL_000456_0001 CGP 8:15417215-16567490
CIL_0001VY CIL_0001VY_0001 CGP 8:16107878-17002181

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005581 IEA collagen trimer
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006898 IEA receptor-mediated endocytosis
GO:0007165 IEA signal transduction
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0010886 ISS positive regulation of cholesterol storage
GO:0016020 IEA membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 ISS cholesterol transport
GO:0030666 TAS endocytic vesicle membrane
GO:0034362 IEA low-density lipoprotein particle
GO:0034381 ISS plasma lipoprotein particle clearance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026021 Msr1-201 protein_coding Mus_musculus 0 865

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