C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: macrophage scavenger receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381998 MSR1-003 ENSG00000038945 9606 - 8:16139319-16192659 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381998
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381998 11.153±0.00 1.428±0.00 0.462±0.00 1.321±0.00 4.094±0.91 1.152±0.00 0.870±0.19 1.974±0.00 1.389±0.81 20.131±6.34 0.286±0.00 2.049±0.47 3.575±0.85 0.856±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000456 CIL_000456_0001 CGP 8:15417215-16567490
CIL_0001VY CIL_0001VY_0001 CGP 8:16107878-17002181

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005044 IEA scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005581 IEA collagen trimer
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006898 IEA receptor-mediated endocytosis
GO:0007165 IEA signal transduction
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0010886 ISS positive regulation of cholesterol storage
GO:0016020 IEA membrane
GO:0030169 ISS low-density lipoprotein particle binding
GO:0030301 ISS cholesterol transport
GO:0030666 TAS endocytic vesicle membrane
GO:0034362 IEA low-density lipoprotein particle
GO:0034381 ISS plasma lipoprotein particle clearance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000140494 Hspa14-003 nonsense_mediated_decay Mus_musculus 0.0000003 62
ENSMUST00000124331 Hspa14-002 nonsense_mediated_decay Mus_musculus 0.0000003 62
ENSMUST00000113827 Brwd1-003 protein_coding Mus_musculus 0.00001 57
ENSMUST00000134412 Serf2-002 retained_intron Mus_musculus 0.0002 53
ENSMUST00000139253 Serf2-001 protein_coding Mus_musculus 0.0002 53
ENSMUST00000004428 Clcn5-001 protein_coding Mus_musculus 0.0002 53

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