C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 28
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000048028 USP28 9606 - 11:113797874-113875570 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000003302 USP28-001 113797874-113875570 protein_coding
  ENST00000535607 USP28-011 113817706-113833517 nonsense_mediated_decay
  ENST00000537490 USP28-013 113817831-113830976 nonsense_mediated_decay
  ENST00000537642 USP28-009 113829221-113875496 protein_coding
  ENST00000537706 USP28-002 113813755-113875528 protein_coding
  ENST00000538224 USP28-014 113804928-113809175 protein_coding
  ENST00000538475 USP28-012 113812279-113833470 protein_coding
  ENST00000540438 USP28-005 113799062-113875566 nonsense_mediated_decay
  ENST00000540925 USP28-007 113852527-113875536 protein_coding
  ENST00000542033 USP28-003 113830883-113875533 processed_transcript
  ENST00000544272 USP28-015 113798979-113801701 retained_intron
  ENST00000544750 USP28-008 113852622-113875533 protein_coding
  ENST00000544967 USP28-006 113798092-113829467 protein_coding
  ENST00000545540 USP28-004 113798805-113875570 protein_coding
  ENST00000545608 USP28-010 113815264-113833552 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000003302ENST00000537706ENST00000540438ENST00000542033ENST00000544272ENST00000544967ENST00000545540
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000003302 N/A N/A N/A N/A 0.545±0.00 1.130±0.00 7.443±5.71 N/A 1.075±0.00 N/A 12.752±0.00 2.767±0.00 0.478±0.00 1.167±0.00
ENST00000537706 N/A N/A N/A 0.920±0.00 1.825±0.00 1.009±0.00 3.928±0.00 N/A N/A 1.946±0.00 N/A 1.337±0.00 N/A N/A
ENST00000540438 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.806±0.00 N/A N/A
ENST00000542033 N/A N/A N/A 2.952±0.00 5.164±0.00 2.842±0.00 12.424±0.00 1.548±0.00 6.089±0.00 3.745±0.00 11.013±0.00 5.818±0.00 N/A N/A
ENST00000544272 N/A N/A 4.393±0.00 N/A N/A N/A N/A 3.200±0.00 N/A N/A N/A N/A N/A N/A
ENST00000544967 0.846±0.00 1.675±0.00 0.379±0.00 0.659±0.32 1.427±0.54 2.784±0.00 5.425±0.00 1.757±0.00 0.840±0.10 1.388±0.16 5.004±0.00 3.344±1.00 1.197±0.28 4.151±0.42
ENST00000545540 N/A N/A N/A 0.299±0.00 N/A N/A 3.847±0.00 0.929±0.00 1.034±0.00 N/A N/A 1.421±0.24 0.601±0.24 1.143±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C0 CIL_0002C0_0002 CGP 11:113797874-113946565

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 IMP DNA damage checkpoint
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006281 IEA DNA repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0008234 IEA cysteine-type peptidase activity
GO:0008283 IMP cell proliferation
GO:0010212 IDA response to ionizing radiation
GO:0016579 IDA protein deubiquitination
GO:0034644 IDA cellular response to UV
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043234 IDA protein complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008880 usp28 ubiquitin specific peptidase 28 protein_coding Danio_rerio
ENSMUSG00000032267 Usp28 ubiquitin specific peptidase 28 protein_coding Mus_musculus

Loading