C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thromboxane A synthase 1 (platelet)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000059377 TBXAS1 9606 + 7:139777051-140020325 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263552 TBXAS1-201 139778248-140020323 protein_coding
  ENST00000336425 TBXAS1-001 139778400-140020293 protein_coding
  ENST00000411653 TBXAS1-005 139829264-140020325 protein_coding
  ENST00000414041 TBXAS1-013 139829302-139936235 nonsense_mediated_decay
  ENST00000414508 TBXAS1-202 139829153-140020323 protein_coding
  ENST00000416849 TBXAS1-203 139778248-140020323 protein_coding
  ENST00000422328 TBXAS1-006 139829247-140020291 nonsense_mediated_decay
  ENST00000425687 TBXAS1-002 139778248-140020289 protein_coding
  ENST00000438104 TBXAS1-011 139778338-139936307 protein_coding
  ENST00000448866 TBXAS1-003 139829224-140020293 protein_coding
  ENST00000455353 TBXAS1-008 139829254-139914029 protein_coding
  ENST00000458722 TBXAS1-004 139829254-140020279 protein_coding
  ENST00000462053 TBXAS1-016 139777147-139797484 processed_transcript
  ENST00000462275 TBXAS1-007 139829273-140016829 processed_transcript
  ENST00000469630 TBXAS1-015 139953435-139963051 retained_intron
  ENST00000473948 TBXAS1-018 139778136-139782729 processed_transcript
  ENST00000474763 TBXAS1-017 139778254-139797484 processed_transcript
  ENST00000476637 TBXAS1-014 139829271-139953517 retained_intron
  ENST00000481440 TBXAS1-010 139778256-139797483 processed_transcript
  ENST00000492560 TBXAS1-012 139829249-139875892 retained_intron
  ENST00000493340 TBXAS1-009 139777051-139789622 processed_transcript
  ENST00000494876 TBXAS1-019 139957581-139962236 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336425ENST00000411653ENST00000422328ENST00000425687ENST00000438104ENST00000448866ENST00000455353ENST00000458722ENST00000462275ENST00000469630ENST00000474763ENST00000476637ENST00000493340ENST00000494876
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336425 N/A N/A N/A N/A 1.454±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.414±0.00
ENST00000411653 N/A N/A 0.617±0.00 1.689±0.04 N/A N/A 0.450±0.00 2.433±0.00 1.693±0.00 N/A N/A 0.743±0.00 N/A N/A
ENST00000422328 N/A N/A N/A N/A N/A N/A 0.346±0.00 N/A N/A 1.640±0.00 N/A N/A N/A N/A
ENST00000425687 N/A N/A N/A N/A N/A 0.356±0.00 0.555±0.00 N/A N/A N/A N/A 2.776±0.00 N/A N/A
ENST00000438104 N/A N/A N/A N/A 2.620±0.00 N/A N/A N/A N/A N/A N/A 4.804±0.00 N/A N/A
ENST00000448866 7.434±0.00 10.602±0.00 N/A 3.252±0.00 2.536±1.06 0.803±0.00 0.649±0.38 4.507±0.00 4.655±0.00 8.602±5.35 0.507±0.00 4.504±2.54 13.012±1.49 1.090±0.00
ENST00000455353 N/A N/A N/A N/A N/A N/A N/A N/A 0.952±0.00 N/A 0.043±0.00 N/A N/A 0.268±0.00
ENST00000458722 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.494±0.00
ENST00000462275 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.262±0.00 N/A N/A N/A
ENST00000469630 N/A N/A N/A 0.308±0.00 N/A 0.185±0.00 N/A N/A N/A 2.764±0.00 N/A 2.304±0.72 N/A 0.120±0.00
ENST00000474763 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.341±0.00
ENST00000476637 N/A N/A N/A N/A 2.920±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000493340 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.374±0.00 N/A N/A N/A
ENST00000494876 N/A N/A N/A N/A N/A N/A 2.887±0.00 N/A N/A N/A N/A 7.738±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00030C CIL_00030C_0001 CGP 7:139523856-139777778
CIL_00023M CIL_00023M_0002 CGP 7:139561570-140020325
CIL_000309 CIL_000309_0002 CGP 7:139777051-140063721

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004796 IEA thromboxane-A synthase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006690 TAS icosanoid metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0016021 IEA integral component of membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0019369 TAS arachidonic acid metabolic process
GO:0019371 TAS cyclooxygenase pathway
GO:0020037 IEA heme binding
GO:0030644 IEA cellular chloride ion homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0045907 IEA positive regulation of vasoconstriction
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002249 tbxas1 thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) protein_coding Danio_rerio
ENSMUSG00000029925 Tbxas1 thromboxane A synthase 1, platelet protein_coding Mus_musculus

Loading