C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thromboxane A synthase 1, platelet
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029925 Tbxas1 10090 + 6:38875404-39084585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003017 Tbxas1-001 38918980-39084585 protein_coding
  ENSMUST00000159226 Tbxas1-004 38919005-39029153 retained_intron
  ENSMUST00000160963 Tbxas1-006 38941401-39001363 protein_coding
  ENSMUST00000161360 Tbxas1-005 38983310-39073206 retained_intron
  ENSMUST00000161781 Tbxas1-002 38919024-39084585 retained_intron
  ENSMUST00000162521 Tbxas1-003 38875404-38952973 protein_coding
  ENSMUST00000162656 Tbxas1-007 38971865-38983526 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003017ENSMUST00000159226ENSMUST00000161360ENSMUST00000161781ENSMUST00000162521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003017 3.568±0.63 2.485±0.29 1.512±0.05 0.374±0.26 4.112±0.37 1.068±0.37 0.580±0.11 2.763±0.00 2.458±2.17 3.549±0.69 0.221±0.08 2.216±0.60 0.457±0.25 0.123±0.08
ENSMUST00000159226 N/A N/A N/A N/A N/A N/A N/A N/A 0.124±0.04 N/A N/A N/A N/A 0.069±0.03
ENSMUST00000161360 N/A 0.325±0.00 N/A 0.058±0.00 N/A 0.266±0.00 0.110±0.00 N/A 0.049±0.00 N/A 0.045±0.01 N/A N/A 0.032±0.00
ENSMUST00000161781 0.880±0.26 0.447±0.08 0.534±0.23 0.081±0.00 0.921±0.21 0.339±0.15 0.175±0.05 1.158±0.11 0.444±0.47 0.637±0.14 0.064±0.02 0.333±0.10 0.061±0.03 0.034±0.03
ENSMUST00000162521 N/A N/A N/A N/A N/A N/A N/A N/A 0.224±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00030C CIL_00030C_0002 CGP 6:38663069-38876165
CIL_00023M CIL_00023M_0003 CGP 6:38694390-39084585
CIL_000309 CIL_000309_0003 CGP 6:38875404-39118349

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001516 IEA prostaglandin biosynthetic process
GO:0004497 IEA monooxygenase activity
GO:0004796 IMP thromboxane-A synthase activity
GO:0005506 IEA iron ion binding
GO:0005783 IEA endoplasmic reticulum
GO:0016021 IEA integral component of membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0030644 IEA cellular chloride ion homeostasis
GO:0045907 IEA positive regulation of vasoconstriction
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002249 tbxas1 thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) protein_coding Danio_rerio
ENSG00000059377 TBXAS1 thromboxane A synthase 1 (platelet) protein_coding Homo_sapiens

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