C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000061273 HDAC7 9606 - 12:47782722-47833132 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000080059 HDAC7-001 47782722-47819785 protein_coding
  ENST00000354334 HDAC7-002 47782722-47819866 protein_coding
  ENST00000380610 HDAC7-029 47783721-47802512 protein_coding
  ENST00000417107 HDAC7-009 47798560-47819980 protein_coding
  ENST00000417902 HDAC7-018 47798118-47819961 protein_coding
  ENST00000421231 HDAC7-016 47797430-47813051 protein_coding
  ENST00000422254 HDAC7-021 47797107-47813051 protein_coding
  ENST00000425451 HDAC7-017 47795377-47819883 nonsense_mediated_decay
  ENST00000427332 HDAC7-013 47783841-47820612 protein_coding
  ENST00000430670 HDAC7-019 47795667-47819875 protein_coding
  ENST00000433685 HDAC7-011 47798188-47820573 protein_coding
  ENST00000434070 HDAC7-014 47797384-47833132 protein_coding
  ENST00000440293 HDAC7-020 47797118-47819886 protein_coding
  ENST00000445237 HDAC7-015 47798640-47813484 protein_coding
  ENST00000447463 HDAC7-012 47797384-47820601 protein_coding
  ENST00000450805 HDAC7-010 47798114-47819262 protein_coding
  ENST00000459625 HDAC7-007 47782726-47793498 retained_intron
  ENST00000463732 HDAC7-023 47794836-47795850 retained_intron
  ENST00000470668 HDAC7-005 47782726-47798189 retained_intron
  ENST00000471235 HDAC7-008 47785451-47788169 retained_intron
  ENST00000477203 HDAC7-030 47783674-47799140 nonsense_mediated_decay
  ENST00000477937 HDAC7-026 47790377-47793386 processed_transcript
  ENST00000485796 HDAC7-022 47794869-47797492 nonsense_mediated_decay
  ENST00000488927 HDAC7-027 47788096-47792000 nonsense_mediated_decay
  ENST00000491464 HDAC7-024 47794807-47795604 retained_intron
  ENST00000547259 HDAC7-004 47783800-47786667 nonsense_mediated_decay
  ENST00000548080 HDAC7-031 47783516-47792004 protein_coding
  ENST00000548938 HDAC7-003 47782726-47793542 nonsense_mediated_decay
  ENST00000549883 HDAC7-033 47783638-47785381 processed_transcript
  ENST00000552960 HDAC7-028 47783651-47819886 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000080059ENST00000354334ENST00000459625ENST00000548938
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000080059 17.963±0.00 15.860±0.00 N/A N/A 12.045±0.00 N/A N/A 3.648±0.00 13.239±11.37 23.796±6.05 19.019±4.08 N/A
ENST00000354334 23.324±0.00 20.052±0.00 3.265±0.00 10.004±8.37 15.275±0.00 11.118±0.00 N/A 2.308±0.00 24.565±0.00 39.127±0.00 16.118±2.33 10.808±0.00
ENST00000459625 N/A N/A N/A 1.189±0.00 N/A N/A N/A N/A 1.160±0.00 N/A N/A N/A
ENST00000548938 N/A 22.436±0.00 N/A N/A 2.443±0.00 N/A 1.466±0.00 N/A 22.313±0.00 29.273±3.10 26.384±0.00 10.581±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OC CIL_0002OC_0001 CGP 12:47734672-47782753
CIL_0003DF CIL_0003DF_0002 CGP 12:47753916-47833132
CIL_0003DI CIL_0003DI_0002 CGP 12:47782722-47943048

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001570 IEA vasculogenesis
GO:0003682 IEA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0004407 IEA histone deacetylase activity
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007043 IEA cell-cell junction assembly
GO:0007219 TAS Notch signaling pathway
GO:0016568 IEA chromatin modification
GO:0016575 IEA histone deacetylation
GO:0019901 IPI protein kinase binding
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032703 IDA negative regulation of interleukin-2 production
GO:0033613 IPI activating transcription factor binding
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070491 IPI repressing transcription factor binding
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071889 IDA 14-3-3 protein binding
GO:0090050 IMP positive regulation of cell migration involved in sprouting angiogenesis
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073850 HDAC7 histone deacetylase 7 protein_coding Danio_rerio
ENSDARG00000093701 histone deacetylase 7 protein_coding Danio_rerio
ENSMUSG00000022475 Hdac7 histone deacetylase 7 protein_coding Mus_musculus

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