C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022475 Hdac7 10090 - 15:97792664-97844502 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079838 Hdac7-006 97792664-97831494 protein_coding
  ENSMUST00000088402 Hdac7-005 97792681-97831767 protein_coding
  ENSMUST00000116408 Hdac7-001 97792666-97844502 protein_coding
  ENSMUST00000116409 Hdac7-002 97792690-97844302 protein_coding
  ENSMUST00000118294 Hdac7-007 97792709-97831494 protein_coding
  ENSMUST00000119670 Hdac7-003 97792688-97844269 protein_coding
  ENSMUST00000120683 Hdac7-004 97792709-97844164 protein_coding
  ENSMUST00000121514 Hdac7-008 97792688-97814863 protein_coding
  ENSMUST00000134258 Hdac7-011 97801282-97807984 protein_coding
  ENSMUST00000135651 Hdac7-012 97799609-97807633 protein_coding
  ENSMUST00000151334 Hdac7-010 97792687-97794445 retained_intron
  ENSMUST00000156045 Hdac7-009 97797799-97831469 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079838ENSMUST00000088402ENSMUST00000116409ENSMUST00000118294ENSMUST00000121514ENSMUST00000151334ENSMUST00000156045
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079838 16.890±0.44 30.058±8.18 N/A N/A 25.985±5.41 8.293±0.88 8.157±0.04 9.668±0.00 N/A 47.686±11.39 N/A 25.350±3.81 N/A 1.193±0.00
ENSMUST00000088402 10.356±0.33 N/A 12.143±1.13 11.523±1.74 11.583±0.00 N/A 6.754±1.15 N/A 3.122±0.00 17.387±0.25 3.862±0.32 5.077±0.00 1.427±0.55 1.233±0.00
ENSMUST00000116409 N/A 17.127±0.42 N/A 10.542±0.00 N/A N/A N/A N/A N/A N/A N/A 11.898±0.00 1.119±0.00 1.192±0.00
ENSMUST00000118294 N/A N/A N/A N/A N/A N/A 3.993±0.00 N/A N/A N/A N/A N/A 1.360±0.30 N/A
ENSMUST00000121514 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.582±0.00 N/A
ENSMUST00000151334 N/A N/A N/A N/A 24.715±0.00 N/A N/A N/A N/A N/A N/A 17.967±6.35 3.022±1.81 0.719±0.00
ENSMUST00000156045 N/A 30.849±2.01 N/A N/A 31.461±0.58 6.495±0.55 N/A N/A N/A 37.806±13.69 N/A 15.434±1.04 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OC CIL_0002OC_0002 CGP 15:97744770-97792692
CIL_0003DF CIL_0003DF_0003 CGP 15:97784355-97844502
CIL_0003DI CIL_0003DI_0003 CGP 15:97792664-97910630

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 TAS histone deacetylase complex
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001570 IMP vasculogenesis
GO:0003682 IDA chromatin binding
GO:0003714 IDA transcription corepressor activity
GO:0004407 TAS histone deacetylase activity
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006954 TAS inflammatory response
GO:0007043 IMP cell-cell junction assembly
GO:0007399 TAS nervous system development
GO:0008134 TAS transcription factor binding
GO:0008152 IEA metabolic process
GO:0016568 TAS chromatin modification
GO:0016575 TAS histone deacetylation
GO:0016787 IEA hydrolase activity
GO:0019901 IEA protein kinase binding
GO:0030183 TAS B cell differentiation
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032703 IEA negative regulation of interleukin-2 production
GO:0033613 IEA activating transcription factor binding
GO:0042113 TAS B cell activation
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045843 TAS negative regulation of striated muscle tissue development
GO:0045892 TAS negative regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0070491 IEA repressing transcription factor binding
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0071889 ISS 14-3-3 protein binding
GO:0090050 IEA positive regulation of cell migration involved in sprouting angiogenesis
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073850 HDAC7 histone deacetylase 7 protein_coding Danio_rerio
ENSDARG00000093701 histone deacetylase 7 protein_coding Danio_rerio
ENSG00000061273 HDAC7 histone deacetylase 7 protein_coding Homo_sapiens

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