C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, non-receptor type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070159 PTPN3 9606 - 9:109375466-109498313 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262539 PTPN3-201 109375694-109498313 protein_coding
  ENST00000374541 PTPN3-001 109375700-109498306 protein_coding
  ENST00000412145 PTPN3-202 109375694-109451384 protein_coding
  ENST00000446349 PTPN3-203 109375694-109451384 protein_coding
  ENST00000447271 PTPN3-003 109375466-109378980 processed_transcript
  ENST00000497739 PTPN3-002 109389237-109397770 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374541ENST00000412145ENST00000446349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374541 0.758±0.00 1.105±0.00 3.346±0.00 0.335±0.00 1.401±0.56 0.490±0.00 8.032±0.00 4.498±4.32 N/A 2.255±0.82 1.785±2.06 1.292±0.72 1.484±0.74
ENST00000412145 N/A N/A N/A 0.297±0.00 0.330±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000446349 N/A N/A 2.493±0.00 N/A 0.458±0.00 N/A N/A N/A 0.377±0.00 N/A 0.100±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IY CIL_0001IY_0001 CGP 9:109171975-109498313
CIL_0001GE CIL_0001GE_0001 CGP 9:109375466-109946703

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001784 IPI phosphotyrosine binding
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006470 IEA protein dephosphorylation
GO:0008092 IEA cytoskeletal protein binding
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0017080 IDA sodium channel regulator activity
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045930 IDA negative regulation of mitotic cell cycle
GO:0051045 IMP negative regulation of membrane protein ectodomain proteolysis
GO:0051117 IPI ATPase binding
GO:0097421 IEA liver regeneration
GO:0098902 IDA regulation of membrane depolarization during action potential
GO:2000649 IDA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055784 ptpn3 protein tyrosine phosphatase, non-receptor type 3 protein_coding Danio_rerio
ENSMUSG00000038764 Ptpn3 protein tyrosine phosphatase, non-receptor type 3 protein_coding Mus_musculus

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