C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, non-receptor type 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038764 Ptpn3 10090 - 4:57190841-57301837 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075637 Ptpn3-001 57190841-57301837 protein_coding
  ENSMUST00000123664 Ptpn3-004 57218347-57222054 processed_transcript
  ENSMUST00000130900 Ptpn3-002 57265058-57301507 protein_coding
  ENSMUST00000150445 Ptpn3-006 57254917-57300915 processed_transcript
  ENSMUST00000151964 Ptpn3-005 57270050-57300756 protein_coding
  ENSMUST00000153926 Ptpn3-003 57245051-57300375 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000075637
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000075637 0.687±0.19 2.647±0.00 0.206±0.00 1.154±0.00 3.774±1.43 1.602±0.58 1.618±0.33 1.040±0.58 0.957±0.45 1.075±0.55 0.710±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001IY CIL_0001IY_0002 CGP 4:56991972-57301837
CIL_0001GE CIL_0001GE_0002 CGP 4:57190841-57712016

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001784 IEA phosphotyrosine binding
GO:0004725 ISS protein tyrosine phosphatase activity
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0008092 IEA cytoskeletal protein binding
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0017080 IEA sodium channel regulator activity
GO:0019898 IEA extrinsic component of membrane
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0045930 IEA negative regulation of mitotic cell cycle
GO:0051045 IEA negative regulation of membrane protein ectodomain proteolysis
GO:0051117 IEA ATPase binding
GO:0097421 IEA liver regeneration
GO:0098902 IEA regulation of membrane depolarization during action potential
GO:2000649 IEA regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055784 ptpn3 protein tyrosine phosphatase, non-receptor type 3 protein_coding Danio_rerio
ENSG00000070159 PTPN3 protein tyrosine phosphatase, non-receptor type 3 protein_coding Homo_sapiens

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