C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2K
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000078140 UBE2K 9606 + 4:39698044-39782792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261427 UBE2K-001 39698044-39782792 protein_coding
  ENST00000438068 UBE2K-002 39698139-39779992 processed_transcript
  ENST00000445950 UBE2K-006 39698176-39779983 protein_coding
  ENST00000503368 UBE2K-005 39698163-39778710 protein_coding
  ENST00000510719 UBE2K-007 39698328-39778633 nonsense_mediated_decay
  ENST00000510934 UBE2K-004 39698109-39778384 protein_coding
  ENST00000513231 UBE2K-003 39698139-39778607 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261427ENST00000503368ENST00000510934ENST00000513231
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261427 7.604±0.00 9.455±0.00 3.105±0.00 14.349±3.13 8.032±1.97 5.935±1.95 4.026±1.54 10.341±2.52 6.539±0.44 0.646±0.00 7.300±0.00 6.909±2.13 7.265±2.30 6.343±0.00
ENST00000503368 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.468±0.00 N/A
ENST00000510934 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.027±0.00 N/A N/A N/A 22.991±5.28
ENST00000513231 16.096±0.00 N/A N/A N/A N/A 15.160±0.00 14.531±0.00 N/A 13.861±0.00 18.032±0.00 N/A 14.806±0.00 24.890±0.00 22.122±1.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TW CIL_0002TW_0002 CGP 4:39546330-39782792
CIL_0002TZ CIL_0002TZ_0002 CGP 4:39698044-39977956

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0008152 IEA metabolic process
GO:0016881 IEA acid-amino acid ligase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032434 IEA regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034450 IDA ubiquitin-ubiquitin ligase activity
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070062 IDA extracellular vesicular exosome
GO:0070936 IDA protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013505 ube2kb ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) protein_coding Danio_rerio
ENSDARG00000089055 ube2ka ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) protein_coding Danio_rerio
ENSMUSG00000029203 Ube2k ubiquitin-conjugating enzyme E2K protein_coding Mus_musculus

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