C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2K
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029203 Ube2k 10090 + 5:65537233-65598988 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031105 Ube2k-004 65537352-65595047 nonsense_mediated_decay
  ENSMUST00000122141 Ube2k-003 65537300-65596393 protein_coding
  ENSMUST00000131873 Ube2k-002 65537277-65595711 processed_transcript
  ENSMUST00000142407 Ube2k-001 65537233-65598988 protein_coding
  ENSMUST00000146799 Ube2k-005 65591596-65595145 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031105ENSMUST00000122141ENSMUST00000131873ENSMUST00000142407
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031105 9.887±0.59 3.629±0.00 19.803±0.00 47.073±0.00 9.775±3.46 N/A 6.952±1.93 10.721±1.49 9.190±2.33 N/A 11.035±1.55 29.719±16.81 60.756±32.72 260.527±0.00
ENSMUST00000122141 N/A 3.612±0.70 5.278±0.00 N/A N/A N/A N/A 4.610±2.00 4.286±1.86 N/A N/A N/A N/A N/A
ENSMUST00000131873 5.872±0.58 4.578±0.17 4.860±0.00 5.606±0.00 4.974±1.04 N/A 6.411±0.89 7.980±1.04 7.240±4.30 N/A 9.731±0.66 8.774±1.66 14.197±3.22 24.844±0.00
ENSMUST00000142407 8.882±2.04 6.829±1.46 6.393±0.77 16.807±8.13 6.972±4.02 9.670±0.72 3.107±0.40 6.792±1.25 4.828±1.24 11.949±0.24 2.609±0.26 11.908±4.81 3.346±1.77 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TW CIL_0002TW_0003 CGP 5:65446844-65598988
CIL_0002TZ CIL_0002TZ_0003 CGP 5:65537233-65697856

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 TAS ubiquitin-protein transferase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0016567 TAS protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0031625 ISS ubiquitin protein ligase binding
GO:0032434 IDA regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034450 IEA ubiquitin-ubiquitin ligase activity
GO:0070059 IEA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070062 IEA extracellular vesicular exosome
GO:0070936 ISS protein K48-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013505 ube2kb ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) protein_coding Danio_rerio
ENSDARG00000089055 ube2ka ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast) protein_coding Danio_rerio
ENSG00000078140 UBE2K ubiquitin-conjugating enzyme E2K protein_coding Homo_sapiens

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