C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 4 (sodium bicarbonate cotransporter), member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000080493 SLC4A4 9606 + 4:71187286-71572087 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264485 SLC4A4-002 71187286-71569717 protein_coding
  ENST00000340595 SLC4A4-001 71339053-71572087 protein_coding
  ENST00000351898 SLC4A4-003 71187327-71568458 protein_coding
  ENST00000425175 SLC4A4-201 71187286-71572087 protein_coding
  ENST00000512686 SLC4A4-004 71339053-71473319 protein_coding
  ENST00000514331 SLC4A4-005 71255218-71473307 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000264485ENST00000340595ENST00000351898ENST00000425175ENST00000512686ENST00000514331
Transcript ID Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000264485 N/A N/A N/A 6.698±0.00 0.504±0.00 N/A N/A N/A N/A N/A N/A
ENST00000340595 11.138±0.00 2.135±0.00 0.611±0.00 N/A 1.036±0.00 18.165±0.00 0.673±0.00 0.129±0.00 N/A N/A 0.068±0.00
ENST00000351898 N/A N/A N/A N/A N/A N/A 0.780±0.00 N/A N/A N/A 0.038±0.00
ENST00000425175 N/A N/A N/A N/A N/A N/A N/A N/A 0.271±0.00 N/A 0.343±0.00
ENST00000512686 24.305±0.00 N/A N/A N/A N/A N/A N/A N/A 0.057±0.00 N/A N/A
ENST00000514331 N/A 4.094±0.00 N/A N/A N/A N/A N/A N/A N/A 0.223±0.00 0.325±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000D8 CIL_0000D8_0001 CGP 4:70992538-71572087
CIL_0000D9 CIL_0000D9_0001 CGP 4:71187286-71804041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005215 IEA transporter activity
GO:0005452 IEA inorganic anion exchanger activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 TAS ion transport
GO:0006814 IEA sodium ion transport
GO:0006820 IEA anion transport
GO:0008509 IEA anion transmembrane transporter activity
GO:0008510 IMP sodium:bicarbonate symporter activity
GO:0015701 TAS bicarbonate transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0035725 IMP sodium ion transmembrane transport
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013730 slc4a4a solute carrier family 4, member 4a protein_coding Danio_rerio
ENSDARG00000044808 slc4a4b solute carrier family 4, sodium bicarbonate cotransporter, member 4b protein_coding Danio_rerio
ENSMUSG00000060961 Slc4a4 solute carrier family 4 (anion exchanger), member 4 protein_coding Mus_musculus

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