C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, beta 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000082781 ITGB5 9606 - 3:124761948-124901418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296181 ITGB5-001 124761948-124887297 protein_coding
  ENST00000460797 ITGB5-002 124762948-124770182 retained_intron
  ENST00000461306 ITGB5-005 124764457-124780704 processed_transcript
  ENST00000465464 ITGB5-003 124821331-124887827 nonsense_mediated_decay
  ENST00000474838 ITGB5-007 124796540-124809398 processed_transcript
  ENST00000476988 ITGB5-009 124817621-124833020 processed_transcript
  ENST00000481591 ITGB5-008 124766230-124821458 protein_coding
  ENST00000483168 ITGB5-004 124848359-124887684 protein_coding
  ENST00000488466 ITGB5-010 124773819-124848451 protein_coding
  ENST00000496703 ITGB5-011 124796591-124841551 protein_coding
  ENST00000608107 ITGB5-015 124848419-124878719 protein_coding
  ENST00000608657 ITGB5-013 124841421-124901418 protein_coding
  ENST00000608945 ITGB5-014 124894452-124901344 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296181ENST00000461306ENST00000476988ENST00000481591ENST00000488466ENST00000496703
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296181 56.533±0.00 13.309±0.00 2.337±0.00 2.975±1.84 22.670±16.88 21.879±0.00 7.779±6.37 25.802±0.00 9.259±7.80 12.978±10.84 7.684±6.44 13.383±8.99 45.664±8.78 6.380±5.41
ENST00000461306 N/A N/A N/A 12.298±0.00 102.270±0.00 46.946±0.00 N/A N/A N/A N/A N/A N/A N/A 27.210±0.00
ENST00000476988 N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.029±0.00 N/A N/A N/A N/A
ENST00000481591 67.435±0.00 N/A N/A 5.536±0.00 N/A 13.924±6.90 17.135±0.00 7.561±0.00 N/A N/A 2.075±0.00 5.226±0.00 N/A N/A
ENST00000488466 95.648±0.00 N/A N/A N/A 61.524±0.00 33.843±0.00 N/A 7.566±0.00 N/A 6.176±0.00 2.682±0.00 28.753±0.00 76.585±0.00 11.054±4.77
ENST00000496703 N/A N/A N/A 2.014±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HE CIL_0008HE_0001 VISTA 3:124285853-124889070

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004872 IEA receptor activity
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006936 TAS muscle contraction
GO:0007155 IEA cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007229 IEA:IMP integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IEA integrin complex
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0030198 TAS extracellular matrix organization
GO:0031252 IEA cell leading edge
GO:0034684 IDA integrin alphav-beta5 complex
GO:0035987 IEP endodermal cell differentiation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043149 IMP stress fiber assembly
GO:0043235 IDA receptor complex
GO:0045335 TAS phagocytic vesicle
GO:0070062 IDA extracellular vesicular exosome
GO:0090136 IMP epithelial cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012942 itgb5 integrin, beta 5 protein_coding Danio_rerio
ENSMUSG00000022817 Itgb5 integrin beta 5 protein_coding Mus_musculus

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