C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, beta 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296181 ITGB5-001 ENSG00000082781 9606 - 3:124761948-124887297 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296181
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296181 56.533±0.00 13.309±0.00 2.337±0.00 2.975±1.84 22.670±16.88 21.879±0.00 7.779±6.37 25.802±0.00 9.259±7.80 12.978±10.84 7.684±6.44 13.383±8.99 45.664±8.78 6.380±5.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HE CIL_0008HE_0001 VISTA 3:124285853-124889070

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004872 IEA receptor activity
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006936 TAS muscle contraction
GO:0007155 IEA cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007229 IEA:IMP integrin-mediated signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0008305 IEA integrin complex
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0030198 TAS extracellular matrix organization
GO:0031252 IEA cell leading edge
GO:0034684 IDA integrin alphav-beta5 complex
GO:0035987 IEP endodermal cell differentiation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043149 IMP stress fiber assembly
GO:0043235 IDA receptor complex
GO:0045335 TAS phagocytic vesicle
GO:0070062 IDA extracellular vesicular exosome
GO:0090136 IMP epithelial cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115028 Itgb5-001 protein_coding Mus_musculus 0 2689
ENSMUST00000069345 Itgb5-002 protein_coding Mus_musculus 0 2545
ENSMUST00000134262 Itgb5-004 processed_transcript Mus_musculus 0 590

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