C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 2-oxoglutarate and iron-dependent oxygenase domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087263 OGFOD1 9606 + 16:56451490-56479100 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336111 OGFOD1-002 56451524-56477129 nonsense_mediated_decay
  ENST00000561646 OGFOD1-009 56451521-56467198 protein_coding
  ENST00000562150 OGFOD1-011 56451521-56466203 protein_coding
  ENST00000563733 OGFOD1-005 56451533-56458901 retained_intron
  ENST00000565209 OGFOD1-006 56458129-56466179 processed_transcript
  ENST00000565682 OGFOD1-010 56451523-56462628 nonsense_mediated_decay
  ENST00000566157 OGFOD1-001 56451490-56479100 protein_coding
  ENST00000568172 OGFOD1-008 56451540-56466268 processed_transcript
  ENST00000568397 OGFOD1-003 56451562-56476335 protein_coding
  ENST00000569645 OGFOD1-004 56451556-56453693 retained_intron
  ENST00000569802 OGFOD1-007 56451521-56466183 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336111ENST00000566157ENST00000568397
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336111 6.820±0.00 7.258±0.00 2.064±0.00 11.523±0.00 8.008±0.00 5.345±0.00 2.295±0.00 1.267±0.00 N/A 2.963±0.00 3.924±0.00 6.329±2.28 5.512±1.49 12.844±0.00
ENST00000566157 2.882±0.00 5.367±0.00 N/A 4.276±1.43 2.282±1.05 1.711±0.33 N/A 0.786±0.00 1.552±0.00 N/A N/A 2.810±1.24 2.280±0.36 N/A
ENST00000568397 N/A N/A N/A N/A 3.955±0.00 2.053±0.00 N/A 1.129±0.00 4.290±0.00 N/A N/A N/A 3.063±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00048T CIL_00048T_0001 CGP 16:56361452-56452199
CIL_00048W CIL_00048W_0001 CGP 16:56429133-56479100
CIL_00048V CIL_00048V_0001 CGP 16:56451490-56520283

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006449 IMP regulation of translational termination
GO:0008283 IMP cell proliferation
GO:0010494 IMP cytoplasmic stress granule
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018126 IDA protein hydroxylation
GO:0019511 IDA peptidyl-proline hydroxylation
GO:0031418 IEA L-ascorbic acid binding
GO:0031543 IDA peptidyl-proline dioxygenase activity
GO:0031544 IDA peptidyl-proline 3-dioxygenase activity
GO:0034063 IMP stress granule assembly
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036061 ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 protein_coding Danio_rerio
ENSMUSG00000033009 Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 protein_coding Mus_musculus

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