C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: TPX2, microtubule-associated
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000088325 TPX2 9606 + 20:31739271-31801805 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300403 TPX2-001 31739271-31801805 protein_coding
  ENST00000340513 TPX2-002 31739271-31801805 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300403ENST00000340513
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300403 0.259±0.00 0.191±0.00 0.067±0.00 0.572±0.06 2.503±0.00 3.395±0.00 0.035±0.00 0.031±0.00 0.269±0.22 0.327±0.00 0.268±0.00 15.240±12.57 5.379±1.74 21.570±1.07
ENST00000340513 0.553±0.00 0.757±0.00 N/A 0.140±0.00 1.110±0.00 0.677±0.00 0.408±0.00 0.191±0.00 0.581±0.00 0.877±0.00 0.276±0.00 0.105±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K5 CIL_0008K5_0001 VISTA 20:31303913-31904751
CIL_00089Z CIL_00089Z_0001 VISTA 20:31373735-31977079
CIL_0008N4 CIL_0008N4_0001 VISTA 20:31410024-32010895
CIL_0001A2 CIL_0001A2_0001 CGP 20:31664452-31801805
CIL_000319 CIL_000319_0002 CGP 20:31739271-31834689

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0005515 IPI protein binding
GO:0005524 TAS ATP binding
GO:0005525 TAS GTP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005819 ISS spindle
GO:0005874 IEA microtubule
GO:0006915 IEA apoptotic process
GO:0007067 IEA mitotic nuclear division
GO:0008283 TAS cell proliferation
GO:0015630 IDA microtubule cytoskeleton
GO:0019901 IPI protein kinase binding
GO:0032147 IDA activation of protein kinase activity
GO:0043203 IEA axon hillock
GO:0060236 ISS regulation of mitotic spindle organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078654 tpx2 TPX2, microtubule-associated, homolog (Xenopus laevis) protein_coding Danio_rerio
ENSMUSG00000027469 Tpx2 TPX2, microtubule-associated protein homolog (Xenopus laevis) protein_coding Mus_musculus

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