C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000091879 ANGPT2 9606 - 8:6499651-6563409 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325203 ANGPT2-001 6499651-6563409 protein_coding
  ENST00000338312 ANGPT2-002 6503080-6563044 protein_coding
  ENST00000523120 ANGPT2-003 6507564-6563245 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENST00000325203ENST00000338312ENST00000523120
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENST00000325203 N/A N/A 0.284±0.00 0.474±0.00 1.038±0.00 0.420±0.00 0.376±0.00 0.552±0.00 0.894±0.65 1.337±0.00 0.693±0.00 1.254±0.00
ENST00000338312 8.363±0.00 5.688±0.00 N/A N/A 3.169±0.00 12.431±0.00 N/A N/A N/A 3.247±0.00 2.359±0.00 3.255±0.98
ENST00000523120 N/A N/A N/A N/A 1.118±0.00 N/A N/A 0.376±0.00 1.086±0.00 N/A 1.261±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LC CIL_0000LC_0001 CGP 8:2935353-6643623
CIL_0008KU CIL_0008KU_0001 VISTA 8:6228238-6829442
CIL_00006Z CIL_00006Z_0002 CGP 8:6406592-6643623
CIL_00006Y CIL_00006Y_0002 CGP 8:6499651-6759666

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001666 IEA response to hypoxia
GO:0005102 TAS receptor binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0007281 IEA germ cell development
GO:0007596 TAS blood coagulation
GO:0009314 IEA response to radiation
GO:0009612 IEA response to mechanical stimulus
GO:0009749 IEA response to glucose
GO:0010812 IEA negative regulation of cell-substrate adhesion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0016525 IEA negative regulation of angiogenesis
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031100 IEA organ regeneration
GO:0042995 IEA cell projection
GO:0043537 IDA negative regulation of blood vessel endothelial cell migration
GO:0045766 IEA positive regulation of angiogenesis
GO:0046872 IEA metal ion binding
GO:0048014 IDA Tie signaling pathway
GO:0048514 IEA blood vessel morphogenesis
GO:0050900 TAS leukocyte migration
GO:0050928 IDA negative regulation of positive chemotaxis
GO:0060135 IEA maternal process involved in female pregnancy
GO:0071363 IEA cellular response to growth factor stimulus
GO:0072012 ISS glomerulus vasculature development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014946 angpt2a angiopoietin 2a protein_coding Danio_rerio
ENSMUSG00000031465 Angpt2 angiopoietin 2 protein_coding Mus_musculus

Loading