C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: angiopoietin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031465 Angpt2 10090 - 8:18690263-18741562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033846 Angpt2-001 18690263-18741562 protein_coding
  ENSMUST00000170200 Angpt2-002 18692087-18699547 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033846ENSMUST00000170200
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033846 3.675±0.97 0.989±0.37 3.302±0.68 1.318±0.45 3.780±0.89 0.774±0.19 1.097±0.14 7.186±0.43 0.338±0.21 5.133±1.24 0.551±0.08 5.497±0.90 7.819±3.67 0.267±0.10
ENSMUST00000170200 N/A 1.032±0.00 N/A N/A N/A N/A N/A N/A 0.043±0.00 N/A N/A 13.878±0.00 53.462±36.41 1.865±1.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LC CIL_0000LC_0002 CGP 8:15892537-18803189
CIL_0008KU CIL_0008KU_0002 VISTA 8:18411246-19012747
CIL_00006Z CIL_00006Z_0003 CGP 8:18595131-18803189
CIL_00006Y CIL_00006Y_0003 CGP 8:18690263-18891361

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IGI angiogenesis
GO:0001666 IEA response to hypoxia
GO:0001974 TAS blood vessel remodeling
GO:0005172 TAS vascular endothelial growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005886 IEA plasma membrane
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007281 IEA germ cell development
GO:0007492 TAS endoderm development
GO:0009314 IEA response to radiation
GO:0009612 IEA response to mechanical stimulus
GO:0009749 IEA response to glucose
GO:0010812 IDA negative regulation of cell-substrate adhesion
GO:0014070 IEA response to organic cyclic compound
GO:0014823 IEA response to activity
GO:0016525 IDA negative regulation of angiogenesis
GO:0030097 TAS hemopoiesis
GO:0030971 IEA receptor tyrosine kinase binding
GO:0031100 IEA organ regeneration
GO:0042995 IEA cell projection
GO:0043537 IEA negative regulation of blood vessel endothelial cell migration
GO:0045765 TAS regulation of angiogenesis
GO:0045766 IEA positive regulation of angiogenesis
GO:0046872 IEA metal ion binding
GO:0048014 TAS Tie signaling pathway
GO:0048514 IMP blood vessel morphogenesis
GO:0050928 IEA negative regulation of positive chemotaxis
GO:0060135 IEA maternal process involved in female pregnancy
GO:0071363 IEA cellular response to growth factor stimulus
GO:0072012 IEA glomerulus vasculature development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014946 angpt2a angiopoietin 2a protein_coding Danio_rerio
ENSG00000091879 ANGPT2 angiopoietin 2 protein_coding Homo_sapiens

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