C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B-cell linker
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000095585 BLNK 9606 - 10:96191702-96271587 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000224337 BLNK-001 96191702-96271540 protein_coding
  ENST00000371176 BLNK-002 96191702-96271540 protein_coding
  ENST00000413476 BLNK-201 96191707-96271516 protein_coding
  ENST00000427367 BLNK-202 96191707-96271516 protein_coding
  ENST00000467799 BLNK-004 96204532-96271587 nonsense_mediated_decay
  ENST00000468252 BLNK-007 96204597-96210303 retained_intron
  ENST00000472763 BLNK-005 96215849-96227497 retained_intron
  ENST00000485193 BLNK-006 96199966-96204854 retained_intron
  ENST00000495266 BLNK-003 96238888-96271398 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderColonKidneyLiverOvaryPlacentaENST00000224337ENST00000371176
Transcript ID Adrenal Bladder Colon Kidney Liver Ovary Placenta
ENST00000224337 8.488±0.00 2.528±0.00 N/A 3.883±1.74 9.132±0.00 3.397±0.00 2.312±0.17
ENST00000371176 N/A N/A 1.219±0.00 6.211±0.00 N/A N/A 1.131±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00071R CIL_00071R_0002 CGP 10:96043394-96205288
CIL_0001C3 CIL_0001C3_0002 CGP 10:96129715-96271587
CIL_0001C1 CIL_0001C1_0002 CGP 10:96191702-96338564

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005068 TAS transmembrane receptor protein tyrosine kinase adaptor activity
GO:0005070 IDA SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005622 NAS intracellular
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006954 TAS inflammatory response
GO:0006959 TAS humoral immune response
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0009967 IDA positive regulation of signal transduction
GO:0030183 NAS B cell differentiation
GO:0035556 IDA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042722 blnk B-cell linker protein_coding Danio_rerio
ENSMUSG00000061132 Blnk B cell linker protein_coding Mus_musculus

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