C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRSF protein kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000096063 SRPK1 9606 - 6:35832966-35921342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000346162 SRPK1-003 35833034-35921065 retained_intron
  ENST00000361690 SRPK1-005 35833034-35921047 protein_coding
  ENST00000373821 SRPK1-008 35874240-35895719 processed_transcript
  ENST00000373822 SRPK1-201 35833035-35921065 protein_coding
  ENST00000373825 SRPK1-001 35832966-35921342 protein_coding
  ENST00000423325 SRPK1-002 35833034-35921147 protein_coding
  ENST00000502969 SRPK1-011 35869589-35870990 retained_intron
  ENST00000505885 SRPK1-013 35835428-35838841 retained_intron
  ENST00000507292 SRPK1-012 35856934-35869551 nonsense_mediated_decay
  ENST00000507909 SRPK1-007 35890949-35921095 protein_coding
  ENST00000508473 SRPK1-006 35886726-35921342 nonsense_mediated_decay
  ENST00000510290 SRPK1-010 35869667-35921128 protein_coding
  ENST00000512445 SRPK1-004 35886783-35921072 protein_coding
  ENST00000513367 SRPK1-009 35887825-35921101 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361690ENST00000373822ENST00000373825ENST00000423325ENST00000513367
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361690 4.047±0.00 4.125±0.00 0.630±0.00 4.413±0.15 2.445±0.00 6.803±0.00 2.415±1.66 3.552±1.09 2.524±1.30 2.807±0.00 5.268±3.93 4.787±2.00 2.783±1.29 18.647±0.00
ENST00000373822 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.428±0.00 N/A N/A
ENST00000373825 0.856±0.00 N/A N/A 1.702±0.00 2.821±1.35 2.879±0.00 N/A N/A 1.137±0.00 1.549±0.00 N/A 9.092±6.91 4.130±3.55 27.243±21.29
ENST00000423325 1.773±0.00 N/A N/A N/A 1.033±0.00 N/A N/A 1.223±0.00 1.330±0.00 1.930±0.00 N/A 0.904±0.00 1.066±0.00 N/A
ENST00000513367 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.153±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002O1 CIL_0002O1_0001 CGP 6:35794982-35833874
CIL_0002O2 CIL_0002O2_0001 CGP 6:35805293-35921342
CIL_0002O7 CIL_0002O7_0001 CGP 6:35832966-36024868

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006397 IEA mRNA processing
GO:0006468 IEA protein phosphorylation
GO:0007059 IDA chromosome segregation
GO:0008380 IEA RNA splicing
GO:0016032 IEA viral process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035092 TAS sperm chromatin condensation
GO:0035556 IDA intracellular signal transduction
GO:0044822 IDA poly(A) RNA binding
GO:0045070 IDA positive regulation of viral genome replication
GO:0045071 IDA negative regulation of viral genome replication
GO:0045087 IC innate immune response
GO:0048024 TAS regulation of mRNA splicing, via spliceosome
GO:0050684 IDA regulation of mRNA processing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031560 srpk1b serine/arginine-rich protein specific kinase 1b protein_coding Danio_rerio
ENSDARG00000073997 srpk1a serine/arginine-rich protein specific kinase 1a protein_coding Danio_rerio
ENSMUSG00000004865 Srpk1 serine/arginine-rich protein specific kinase 1 protein_coding Mus_musculus

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