C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich protein specific kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004865 Srpk1 10090 - 17:28587648-28622521 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004987 Srpk1-002 28589591-28607169 nonsense_mediated_decay
  ENSMUST00000114767 Srpk1-005 28620143-28622472 protein_coding
  ENSMUST00000126683 Srpk1-004 28595463-28600886 retained_intron
  ENSMUST00000130643 Srpk1-001 28587648-28622521 protein_coding
  ENSMUST00000136504 Srpk1-007 28589989-28592425 retained_intron
  ENSMUST00000145023 Srpk1-003 28602548-28622451 retained_intron
  ENSMUST00000145730 Srpk1-006 28600336-28601263 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004987ENSMUST00000126683ENSMUST00000130643ENSMUST00000145023ENSMUST00000145730
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004987 4.135±0.40 5.676±1.12 N/A 11.429±3.34 6.362±2.48 6.018±1.10 2.009±0.25 3.757±0.76 3.282±0.86 3.194±0.47 1.503±0.13 9.697±2.86 22.162±8.57 57.805±12.92
ENSMUST00000126683 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.058±0.00 N/A N/A N/A N/A
ENSMUST00000130643 5.521±2.26 1.118±0.15 8.524±0.13 12.352±3.53 3.623±0.81 5.048±1.79 3.359±1.24 6.139±0.93 4.583±2.91 3.477±0.58 3.050±0.27 5.642±2.12 12.667±4.22 20.507±2.41
ENSMUST00000145023 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.000±0.00 15.306±0.00 13.781±0.00 89.374±0.00
ENSMUST00000145730 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 196.563±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008UQ CIL_0008UQ_0002 VISTA 17:28043766-28646334
CIL_0002O2 CIL_0002O2_0002 CGP 17:28575718-28622521
CIL_0002O7 CIL_0002O7_0002 CGP 17:28587648-28689987

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006397 IEA mRNA processing
GO:0006468 IEA protein phosphorylation
GO:0007059 ISS chromosome segregation
GO:0008380 IEA RNA splicing
GO:0030154 IEA cell differentiation
GO:0035556 IDA intracellular signal transduction
GO:0044822 IEA poly(A) RNA binding
GO:0045070 IEA positive regulation of viral genome replication
GO:0045071 IEA negative regulation of viral genome replication
GO:0050684 IDA regulation of mRNA processing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031560 srpk1b serine/arginine-rich protein specific kinase 1b protein_coding Danio_rerio
ENSDARG00000073997 srpk1a serine/arginine-rich protein specific kinase 1a protein_coding Danio_rerio
ENSG00000096063 SRPK1 SRSF protein kinase 1 protein_coding Homo_sapiens

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