C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HscB mitochondrial iron-sulfur cluster co-chaperone
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100209 HSCB 9606 + 22:28742031-28757515 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216027 HSCB-001 28742031-28757510 protein_coding
  ENST00000398941 HSCB-003 28742055-28757515 protein_coding
  ENST00000420442 HSCB-007 28742061-28757213 nonsense_mediated_decay
  ENST00000450178 HSCB-002 28742042-28757510 nonsense_mediated_decay
  ENST00000483861 HSCB-005 28742679-28757210 processed_transcript
  ENST00000485599 HSCB-004 28742151-28745543 processed_transcript
  ENST00000495977 HSCB-006 28742701-28757510 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216027ENST00000398941ENST00000420442ENST00000450178ENST00000483861ENST00000485599ENST00000495977
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216027 N/A N/A N/A 1.845±0.00 N/A 4.307±0.00 1.442±0.94 2.683±1.92 3.818±3.15 3.123±0.00 0.748±0.00 5.456±0.32 3.483±1.15 6.675±0.00
ENST00000398941 2.081±0.00 5.789±0.00 N/A 3.985±0.00 4.105±0.00 4.099±0.00 1.767±0.00 4.345±0.00 2.035±0.00 N/A N/A 4.074±0.00 N/A N/A
ENST00000420442 1.610±0.00 N/A N/A N/A N/A 3.644±0.00 1.438±0.00 N/A N/A 2.144±0.00 0.928±0.00 7.220±0.00 N/A N/A
ENST00000450178 1.064±0.00 N/A 0.361±0.00 0.377±0.00 3.177±0.00 0.380±0.00 N/A N/A N/A 1.609±0.00 1.335±0.00 N/A N/A N/A
ENST00000483861 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.573±0.00 2.757±0.00
ENST00000485599 N/A N/A N/A N/A N/A N/A N/A 1.251±0.00 N/A 0.885±0.00 N/A N/A N/A N/A
ENST00000495977 N/A 3.578±0.00 0.784±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NO CIL_0008NO_0001 VISTA 22:28282570-28883176
CIL_0006WX CIL_0006WX_0002 CGP 22:28687743-28757515

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005739 TAS mitochondrion
GO:0005813 IDA centrosome
GO:0005886 IDA plasma membrane
GO:0006457 IEA protein folding
GO:0016226 IMP iron-sulfur cluster assembly
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0051259 IEA protein oligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075416 HSCB HscB mitochondrial iron-sulfur cluster co-chaperone protein_coding Danio_rerio
ENSMUSG00000043510 Hscb HscB iron-sulfur cluster co-chaperone homolog (E. coli) protein_coding Mus_musculus

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