C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance complex component 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100297 MCM5 9606 + 22:35400063-35425430 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216122 MCM5-001 35400063-35425430 protein_coding
  ENST00000382011 MCM5-002 35400137-35424501 protein_coding
  ENST00000416905 MCM5-008 35400170-35406725 protein_coding
  ENST00000417343 MCM5-012 35400142-35410008 processed_transcript
  ENST00000444778 MCM5-011 35400431-35410872 protein_coding
  ENST00000451351 MCM5-010 35400134-35403257 nonsense_mediated_decay
  ENST00000464908 MCM5-007 35410359-35415908 processed_transcript
  ENST00000465557 MCM5-006 35411439-35416672 processed_transcript
  ENST00000493076 MCM5-004 35410409-35424501 retained_intron
  ENST00000493569 MCM5-005 35411244-35415965 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216122ENST00000382011ENST00000416905ENST00000417343ENST00000493076
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216122 N/A N/A N/A 0.178±0.00 1.205±0.00 0.445±0.00 0.497±0.00 N/A N/A 1.584±0.00 N/A 1.955±0.34 N/A N/A
ENST00000382011 9.677±0.00 25.038±0.00 0.859±0.00 2.371±1.58 5.699±4.95 4.718±2.50 2.337±2.20 3.951±1.91 2.615±2.07 7.910±0.00 4.492±4.27 18.690±18.49 42.595±31.40 28.506±5.95
ENST00000416905 4.837±0.00 N/A N/A 0.653±0.00 4.169±1.85 2.941±0.00 N/A 2.358±0.00 4.179±0.00 N/A 0.764±0.00 7.461±0.00 N/A N/A
ENST00000417343 N/A N/A N/A N/A N/A N/A N/A N/A 1.554±0.00 N/A N/A N/A N/A N/A
ENST00000493076 N/A 3.132±0.00 N/A N/A N/A N/A N/A 0.492±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099W CIL_00099W_0001 VISTA 22:35286634-35891311
CIL_00094Q CIL_00094Q_0001 VISTA 22:35329925-35944605
CIL_0006NI CIL_0006NI_0002 CGP 22:35380361-35425430
CIL_0003GR CIL_0003GR_0001 CGP 22:35400063-35554001

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0003677 IEA DNA binding
GO:0003678 IEA DNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006260 IEA:TAS DNA replication
GO:0006270 IEA DNA replication initiation
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0016020 IDA membrane
GO:0032508 IEA DNA duplex unwinding
GO:0042555 IDA MCM complex
GO:0051301 IEA cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019507 mcm5 MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000005410 Mcm5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae) protein_coding Mus_musculus

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