C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isocitrate dehydrogenase 3 (NAD+) beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101365 IDH3B 9606 - 20:2658395-2664219 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380843 IDH3B-011 2658395-2664219 protein_coding
  ENST00000380851 IDH3B-010 2658395-2664219 protein_coding
  ENST00000462967 IDH3B-008 2660296-2664215 retained_intron
  ENST00000466494 IDH3B-004 2658395-2660308 processed_transcript
  ENST00000466999 IDH3B-009 2659283-2659916 processed_transcript
  ENST00000474315 IDH3B-001 2658395-2664189 protein_coding
  ENST00000477689 IDH3B-003 2658542-2660309 processed_transcript
  ENST00000479376 IDH3B-005 2660032-2660553 processed_transcript
  ENST00000488299 IDH3B-012 2658395-2664188 retained_intron
  ENST00000491065 IDH3B-002 2660505-2664209 retained_intron
  ENST00000492240 IDH3B-007 2658395-2660359 retained_intron
  ENST00000613370 IDH3B-201 2659015-2664219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380843ENST00000380851ENST00000462967ENST00000466494ENST00000474315ENST00000477689ENST00000491065ENST00000613370
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380843 19.653±0.00 25.565±0.00 2.359±0.00 19.759±5.49 10.722±8.85 23.635±0.00 13.319±0.00 19.650±12.76 7.993±4.15 34.999±0.00 10.818±5.92 27.101±15.08 29.165±7.12 20.017±6.90
ENST00000380851 N/A N/A 1.190±0.00 N/A N/A 3.279±0.00 36.564±18.40 N/A N/A 1.421±0.00 8.861±0.00 N/A N/A N/A
ENST00000462967 N/A N/A N/A N/A N/A 4.466±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000466494 N/A N/A N/A N/A 2.908±0.00 4.103±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000474315 16.399±0.00 19.323±0.00 2.278±0.00 12.169±8.93 11.556±8.94 7.655±5.73 N/A 9.829±8.68 4.706±1.09 5.612±0.00 16.736±0.00 10.136±2.05 8.630±3.47 11.185±3.74
ENST00000477689 N/A N/A N/A N/A N/A N/A N/A N/A 6.976±0.00 N/A N/A N/A N/A N/A
ENST00000491065 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.017±0.00 N/A N/A N/A N/A
ENST00000613370 N/A N/A N/A N/A 1.021±0.00 N/A N/A N/A N/A N/A 1.734±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SG CIL_0007SG_0001 VISTA 20:2438562-3039143
CIL_0000FV CIL_0000FV_0001 CGP 20:2652145-2664219
CIL_0000FY CIL_0000FY_0001 CGP 20:2658395-2760108

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004449 IEA isocitrate dehydrogenase (NAD+) activity
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006102 IEA isocitrate metabolic process
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006734 IEA NADH metabolic process
GO:0009055 TAS electron carrier activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044753 idh3b isocitrate dehydrogenase 3 (NAD+) beta protein_coding Danio_rerio
ENSMUSG00000027406 Idh3b isocitrate dehydrogenase 3 (NAD+) beta protein_coding Mus_musculus

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