C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isocitrate dehydrogenase 3 (NAD+) beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000380843 IDH3B-011 ENSG00000101365 9606 - 20:2658395-2664219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380843
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380843 19.653±0.00 25.565±0.00 2.359±0.00 19.759±5.49 10.722±8.85 23.635±0.00 13.319±0.00 19.650±12.76 7.993±4.15 34.999±0.00 10.818±5.92 27.101±15.08 29.165±7.12 20.017±6.90

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SG CIL_0007SG_0001 VISTA 20:2438562-3039143
CIL_0000FV CIL_0000FV_0001 CGP 20:2652145-2664219
CIL_0000FY CIL_0000FY_0001 CGP 20:2658395-2760108

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004449 IEA isocitrate dehydrogenase (NAD+) activity
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006102 IEA isocitrate metabolic process
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006734 IEA NADH metabolic process
GO:0009055 TAS electron carrier activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028892 Idh3b-001 protein_coding Mus_musculus 0 1485
ENSDART00000149371 idh3b-001 protein_coding Danio_rerio 0 538
ENSMUST00000184538 Idh3b-004 nonsense_mediated_decay Mus_musculus 0 351
ENSMUST00000149843 Idh3b-002 retained_intron Mus_musculus 0 276
ENSMUST00000124868 Idh3b-003 retained_intron Mus_musculus 6.00036e-42 176

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