C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinoblastoma binding protein 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000101773 RBBP8 9606 + 18:22798261-23026488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327155 RBBP8-001 22933315-23026486 protein_coding
  ENST00000360790 RBBP8-005 22934750-23026370 protein_coding
  ENST00000399721 RBBP8-003 22933876-22993569 protein_coding
  ENST00000399722 RBBP8-004 22933826-23026488 protein_coding
  ENST00000399725 RBBP8-002 22933841-23026486 protein_coding
  ENST00000577445 RBBP8-017 22968842-22990944 protein_coding
  ENST00000577588 RBBP8-009 22914123-22936940 protein_coding
  ENST00000579124 RBBP8-007 22914121-22949658 protein_coding
  ENST00000580892 RBBP8-013 22946339-22950035 retained_intron
  ENST00000581687 RBBP8-016 23016796-23026488 protein_coding
  ENST00000581819 RBBP8-010 22914139-22968810 protein_coding
  ENST00000582354 RBBP8-008 22914123-22984897 protein_coding
  ENST00000583057 RBBP8-015 22993484-23026467 protein_coding
  ENST00000583594 RBBP8-012 22933881-22937118 protein_coding
  ENST00000583700 RBBP8-011 22798261-22936883 protein_coding
  ENST00000585177 RBBP8-014 22975181-22991026 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000327155ENST00000360790ENST00000399722ENST00000399725ENST00000581687ENST00000582354ENST00000583057
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000327155 0.806±0.00 0.877±0.00 1.680±0.00 0.709±0.00 1.699±0.60 1.942±0.02 0.468±0.12 5.576±0.00 0.863±0.00 2.740±1.55 2.191±0.50 1.597±0.29 2.932±0.51
ENST00000360790 1.203±0.00 1.218±0.00 N/A N/A 0.606±0.00 N/A 0.212±0.00 N/A N/A N/A N/A 0.573±0.00 N/A
ENST00000399722 N/A N/A 0.693±0.00 0.371±0.00 0.682±0.00 N/A 0.399±0.00 N/A N/A 0.391±0.00 N/A N/A 2.340±0.00
ENST00000399725 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.703±0.05 N/A N/A
ENST00000581687 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.884±0.00 N/A N/A
ENST00000582354 N/A N/A 2.243±0.00 N/A N/A N/A N/A N/A 1.199±0.00 1.262±0.00 2.570±0.00 2.937±0.00 10.199±0.00
ENST00000583057 1.177±0.00 2.179±0.00 2.044±0.00 0.395±0.00 1.198±0.00 1.247±0.15 N/A 3.620±3.32 0.917±0.00 2.054±0.00 3.440±1.80 5.166±0.00 11.903±4.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005NS CIL_0005NS_0001 CGP 18:22798261-23260467

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000014 IMP single-stranded DNA endodeoxyribonuclease activity
GO:0000075 TAS cell cycle checkpoint
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000724 IDA double-strand break repair via homologous recombination
GO:0000737 IMP DNA catabolic process, endonucleolytic
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0001835 IEA blastocyst hatching
GO:0003684 IDA damaged DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006281 TAS DNA repair
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007067 IEA mitotic nuclear division
GO:0010792 IMP DNA double-strand break processing involved in repair via single-strand annealing
GO:0017053 IDA transcriptional repressor complex
GO:0031572 IDA G2 DNA damage checkpoint
GO:0051321 IEA meiotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043480 rbbp8 retinoblastoma binding protein 8 protein_coding Danio_rerio
ENSMUSG00000041238 Rbbp8 retinoblastoma binding protein 8 protein_coding Mus_musculus

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