C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mahogunin ring finger 1, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399577 MGRN1-004 ENSG00000102858 9606 + 16:4624868-4690972 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartMuscleOvaryENST00000399577
Transcript ID Brain Breast Colon Heart Muscle Ovary
ENST00000399577 0.409±0.00 0.878±0.00 0.985±0.00 0.195±0.00 0.360±0.00 3.017±2.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007IF CIL_0007IF_0002 CGP 16:4608883-4690974
CIL_00004Z CIL_00004Z_0001 CGP 16:4616493-4695859

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005769 IDA early endosome
GO:0005886 IEA plasma membrane
GO:0006513 IMP protein monoubiquitination
GO:0008270 IEA zinc ion binding
GO:0008333 IMP endosome to lysosome transport
GO:0016020 IDA membrane
GO:0016874 IEA ligase activity
GO:0043951 IDA negative regulation of cAMP-mediated signaling
GO:0045744 IDA negative regulation of G-protein coupled receptor protein signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000070658 Mgrn1-202 protein_coding Mus_musculus 0 1351
ENSMUST00000023159 Mgrn1-201 protein_coding Mus_musculus 0 1336
ENSMUST00000106398 Rnf157-003 protein_coding Mus_musculus 0 455
ENSMUST00000100202 Rnf157-001 protein_coding Mus_musculus 0 455
ENSMUST00000141229 Rnf157-004 processed_transcript Mus_musculus 0 283
ENSMUST00000149147 Rnf157-002 protein_coding Mus_musculus 0 279

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