C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DnaJ (Hsp40) homolog, subfamily A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103423 DNAJA3 9606 + 16:4425805-4456775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262375 DNAJA3-001 4425805-4456775 protein_coding
  ENST00000355296 DNAJA3-002 4425860-4456775 protein_coding
  ENST00000431375 DNAJA3-201 4425805-4456772 protein_coding
  ENST00000570857 DNAJA3-007 4425865-4442308 nonsense_mediated_decay
  ENST00000572009 DNAJA3-011 4434298-4441401 retained_intron
  ENST00000572139 DNAJA3-010 4433846-4441477 processed_transcript
  ENST00000572974 DNAJA3-008 4425868-4431868 processed_transcript
  ENST00000573120 DNAJA3-013 4426048-4437625 retained_intron
  ENST00000574393 DNAJA3-012 4455492-4456775 processed_transcript
  ENST00000574895 DNAJA3-009 4425879-4442393 protein_coding
  ENST00000575106 DNAJA3-006 4425865-4442383 nonsense_mediated_decay
  ENST00000576180 DNAJA3-004 4449554-4456772 retained_intron
  ENST00000576911 DNAJA3-003 4425865-4455951 nonsense_mediated_decay
  ENST00000577083 DNAJA3-005 4440257-4447955 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262375ENST00000355296ENST00000431375ENST00000575106ENST00000576180ENST00000576911
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262375 1.681±0.00 N/A N/A 2.749±0.53 2.932±0.00 3.061±0.31 3.310±2.50 5.693±1.67 4.669±3.40 1.556±0.31 12.044±0.00 3.628±0.94 3.327±0.06 5.563±0.00
ENST00000355296 4.022±0.00 5.010±0.00 0.735±0.00 3.179±0.71 3.624±0.49 2.071±0.14 8.477±5.46 3.629±1.61 6.603±4.85 4.402±0.00 10.200±5.82 8.100±3.96 9.318±5.61 4.767±1.54
ENST00000431375 N/A 4.564±0.00 N/A 4.897±0.00 N/A 4.312±0.00 N/A 4.019±0.00 10.260±0.00 2.391±0.00 8.582±0.00 5.564±0.52 N/A 4.215±0.13
ENST00000575106 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.645±0.00 N/A N/A
ENST00000576180 N/A 2.368±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000576911 4.308±0.00 5.375±0.00 N/A 8.518±0.00 3.885±2.35 3.983±0.00 1.401±0.00 4.737±2.87 1.506±0.00 2.033±0.00 9.348±0.00 9.873±0.00 11.016±0.00 9.314±2.95

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000003 CIL_000003_0002 CGP 16:4371848-4456775
CIL_0002BN CIL_0002BN_0001 CGP 16:4425805-4495763

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005083 IEA small GTPase regulator activity
GO:0005133 IDA interferon-gamma receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 IDA mitochondrial matrix
GO:0005829 IMP cytosol
GO:0005884 IDA actin filament
GO:0006264 IEA mitochondrial DNA replication
GO:0006457 IEA protein folding
GO:0006469 IDA negative regulation of protein kinase activity
GO:0006915 IEA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006924 IEA activation-induced cell death of T cells
GO:0007005 IEA mitochondrion organization
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007528 IDA neuromuscular junction development
GO:0007569 IEA cell aging
GO:0008134 IPI transcription factor binding
GO:0008285 IDA negative regulation of cell proliferation
GO:0008385 IDA IkappaB kinase complex
GO:0009408 IEA response to heat
GO:0019897 ISS extrinsic component of plasma membrane
GO:0019901 IPI protein kinase binding
GO:0030054 IEA cell junction
GO:0030544 IEA Hsp70 protein binding
GO:0030971 IEA receptor tyrosine kinase binding
GO:0031072 IEA heat shock protein binding
GO:0031398 IDA positive regulation of protein ubiquitination
GO:0031594 ISS neuromuscular junction
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0033077 IEA T cell differentiation in thymus
GO:0033256 IDA I-kappaB/NF-kappaB complex
GO:0034341 IDA response to interferon-gamma
GO:0042102 IEA positive regulation of T cell proliferation
GO:0042645 IDA mitochondrial nucleoid
GO:0043065 IDA positive regulation of apoptotic process
GO:0043066 IDA negative regulation of apoptotic process
GO:0043069 IEA negative regulation of programmed cell death
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043154 IDA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045211 ISS postsynaptic membrane
GO:0046872 IEA metal ion binding
GO:0050821 IDA protein stabilization
GO:0051059 IPI NF-kappaB binding
GO:0051082 IEA unfolded protein binding
GO:0060336 IDA negative regulation of interferon-gamma-mediated signaling pathway
GO:0071340 ISS skeletal muscle acetylcholine-gated channel clustering

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058494 dnaja3a DnaJ (Hsp40) homolog, subfamily A, member 3A protein_coding Danio_rerio
ENSDARG00000095983 dnaja3b DnaJ (Hsp40) homolog, subfamily A, member 3B protein_coding Danio_rerio
ENSMUSG00000004069 Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 protein_coding Mus_musculus

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