C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DnaJ (Hsp40) homolog, subfamily A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004069 Dnaja3 10090 + 16:4639989-4707695 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060067 Dnaja3-001 4684070-4707695 protein_coding
  ENSMUST00000115854 Dnaja3-002 4684096-4707695 protein_coding
  ENSMUST00000138495 Dnaja3-003 4684114-4694245 retained_intron
  ENSMUST00000144815 Dnaja3-004 4639989-4687292 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060067ENSMUST00000115854ENSMUST00000138495
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060067 N/A N/A N/A N/A N/A N/A 7.464±0.76 N/A 4.933±0.66 N/A 10.449±1.10 5.844±0.14 8.724±0.00 N/A
ENSMUST00000115854 23.197±2.75 30.064±3.75 17.174±0.41 17.745±5.57 23.757±1.05 16.596±1.19 34.880±3.90 34.506±2.03 22.335±3.76 14.124±0.43 32.187±1.27 21.320±3.85 23.161±13.24 15.771±1.42
ENSMUST00000138495 N/A 42.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009Y CIL_00009Y_0002 CGP 16:4616464-4679777
CIL_00009L CIL_00009L_0002 CGP 16:4626133-4679777
CIL_000003 CIL_000003_0003 CGP 16:4639941-4707695
CIL_0002BN CIL_0002BN_0002 CGP 16:4639989-4719356

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0005083 IDA small GTPase regulator activity
GO:0005133 IEA interferon-gamma receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 IEA mitochondrial matrix
GO:0005829 IDA cytosol
GO:0005884 IEA actin filament
GO:0006264 IMP mitochondrial DNA replication
GO:0006457 IEA protein folding
GO:0006469 IEA negative regulation of protein kinase activity
GO:0006915 IMP apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006924 IMP activation-induced cell death of T cells
GO:0007005 IMP mitochondrion organization
GO:0007264 IDA small GTPase mediated signal transduction
GO:0007528 IMP neuromuscular junction development
GO:0007569 IDA cell aging
GO:0008134 IEA transcription factor binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0008385 IEA IkappaB kinase complex
GO:0009408 IEA response to heat
GO:0019897 IDA extrinsic component of plasma membrane
GO:0019901 IEA protein kinase binding
GO:0030054 IEA cell junction
GO:0030544 IEA Hsp70 protein binding
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031398 IEA positive regulation of protein ubiquitination
GO:0031594 IDA neuromuscular junction
GO:0032088 ISA negative regulation of NF-kappaB transcription factor activity
GO:0033077 IMP T cell differentiation in thymus
GO:0033256 IEA I-kappaB/NF-kappaB complex
GO:0034341 IEA response to interferon-gamma
GO:0042102 IMP positive regulation of T cell proliferation
GO:0042645 IEA mitochondrial nucleoid
GO:0043065 IEA positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043069 IMP negative regulation of programmed cell death
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045211 IDA postsynaptic membrane
GO:0046872 IEA metal ion binding
GO:0050821 IEA protein stabilization
GO:0051059 IEA NF-kappaB binding
GO:0051082 IPI unfolded protein binding
GO:0060336 IEA negative regulation of interferon-gamma-mediated signaling pathway
GO:0071340 IMP skeletal muscle acetylcholine-gated channel clustering

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058494 dnaja3a DnaJ (Hsp40) homolog, subfamily A, member 3A protein_coding Danio_rerio
ENSDARG00000095983 dnaja3b DnaJ (Hsp40) homolog, subfamily A, member 3B protein_coding Danio_rerio
ENSG00000103423 DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 protein_coding Homo_sapiens

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