C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 6 (neurotransmitter transporter), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000103546 SLC6A2 9606 + 16:55655604-55706192 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000219833 SLC6A2-201 55656644-55706192 protein_coding
  ENST00000379906 SLC6A2-001 55656440-55703788 protein_coding
  ENST00000414754 SLC6A2-003 55656110-55703750 protein_coding
  ENST00000561820 SLC6A2-007 55656618-55705648 protein_coding
  ENST00000566163 SLC6A2-006 55656655-55702346 protein_coding
  ENST00000567238 SLC6A2-005 55671671-55703791 protein_coding
  ENST00000568529 SLC6A2-009 55656086-55694113 protein_coding
  ENST00000568655 SLC6A2-008 55656254-55672131 protein_coding
  ENST00000568943 SLC6A2-004 55655604-55702346 protein_coding
  ENST00000574918 SLC6A2-010 55700274-55705853 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000219833ENST00000379906ENST00000414754ENST00000566163ENST00000567238ENST00000568655ENST00000574918
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000219833 N/A N/A N/A N/A N/A N/A N/A 0.050±0.00 N/A N/A 2.985±0.00 N/A
ENST00000379906 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.559±1.75 0.671±0.00
ENST00000414754 N/A N/A 0.067±0.00 N/A N/A N/A 0.010±0.00 N/A 0.079±0.00 0.016±0.00 N/A N/A
ENST00000566163 N/A 0.056±0.00 N/A N/A N/A N/A N/A N/A N/A 0.017±0.00 N/A N/A
ENST00000567238 N/A 0.019±0.00 0.051±0.00 0.024±0.00 0.348±0.00 N/A N/A N/A 0.063±0.00 0.092±0.00 N/A 1.772±0.38
ENST00000568655 N/A N/A N/A N/A N/A 0.262±0.00 N/A N/A N/A N/A N/A N/A
ENST00000574918 0.280±0.00 0.174±0.00 N/A N/A 0.261±0.00 0.066±0.00 0.037±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000988 CIL_000988_0001 VISTA 16:55084120-55684969
CIL_00098D CIL_00098D_0001 VISTA 16:55090504-55691826
CIL_0005R5 CIL_0005R5_0001 CGP 16:55566672-55706192
CIL_00048S CIL_00048S_0001 CGP 16:55655604-55833337

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005333 IEA norepinephrine transmembrane transporter activity
GO:0005334 TAS norepinephrine:sodium symporter activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006810 TAS transport
GO:0006836 IEA neurotransmitter transport
GO:0007268 TAS synaptic transmission
GO:0008504 IDA monoamine transmembrane transporter activity
GO:0009986 IEA cell surface
GO:0015844 IDA monoamine transport
GO:0015874 IEA norepinephrine transport
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043014 IEA alpha-tubulin binding
GO:0045121 IEA membrane raft
GO:0048265 IEA response to pain
GO:0048487 IEA beta-tubulin binding
GO:0055085 IEA:TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016141 slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 protein_coding Danio_rerio
ENSMUSG00000055368 Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 protein_coding Mus_musculus

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