C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 3, subunit E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000104408 EIF3E 9606 - 8:108201216-108435333 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000220849 EIF3E-001 108201743-108248765 protein_coding
  ENST00000518100 EIF3E-006 108235031-108248716 nonsense_mediated_decay
  ENST00000518345 EIF3E-007 108235097-108248717 protein_coding
  ENST00000518442 EIF3E-003 108234284-108248802 retained_intron
  ENST00000518634 EIF3E-017 108241893-108355726 processed_transcript
  ENST00000519030 EIF3E-002 108201780-108248698 protein_coding
  ENST00000519413 EIF3E-014 108216476-108227932 processed_transcript
  ENST00000519517 EIF3E-012 108203470-108231908 processed_transcript
  ENST00000519627 EIF3E-008 108214607-108248719 protein_coding
  ENST00000521297 EIF3E-010 108235094-108248668 protein_coding
  ENST00000521440 EIF3E-011 108233394-108248698 protein_coding
  ENST00000521614 EIF3E-004 108201865-108242833 retained_intron
  ENST00000522088 EIF3E-018 108309022-108435333 processed_transcript
  ENST00000522352 EIF3E-015 108201743-108229136 protein_coding
  ENST00000522445 EIF3E-009 108217381-108248718 nonsense_mediated_decay
  ENST00000522887 EIF3E-005 108235054-108248717 nonsense_mediated_decay
  ENST00000523646 EIF3E-013 108228177-108229398 retained_intron
  ENST00000523674 EIF3E-016 108201216-108203346 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000220849ENST00000519030ENST00000519627ENST00000522445
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000220849 60.708±0.00 59.252±0.00 8.608±0.00 19.984±3.47 52.246±4.88 80.416±48.03 22.016±4.43 34.922±5.56 32.740±12.15 54.517±15.45 31.876±22.40 131.897±40.13 39.731±16.01 63.173±13.10
ENST00000519030 41.211±0.00 48.702±0.00 8.510±0.00 14.189±2.30 35.036±8.50 42.919±23.28 9.962±4.31 17.868±0.07 17.593±3.76 29.787±17.51 13.291±2.21 79.243±64.59 28.823±10.40 40.156±0.00
ENST00000519627 N/A N/A N/A N/A N/A N/A 18.081±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000522445 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 57.548±0.00 37.333±0.00 32.437±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004T1 CIL_0004T1_0002 CGP 8:107899316-108435333
CIL_0004T2 CIL_0004T2_0002 CGP 8:108201216-108486918

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 IMP nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000785 NAS chromatin
GO:0001731 IEA formation of translation preinitiation complex
GO:0003743 IEA:IC translation initiation factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 NAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005852 IEA:NAS eukaryotic translation initiation factor 3 complex
GO:0006412 TAS translation
GO:0006413 IC translational initiation
GO:0006446 IEA:NAS regulation of translational initiation
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016282 IEA eukaryotic 43S preinitiation complex
GO:0016605 IEA:IDA PML body
GO:0033290 IEA eukaryotic 48S preinitiation complex
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045947 NAS negative regulation of translational initiation
GO:0047485 IPI protein N-terminus binding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090697 eif3ea eukaryotic translation initiation factor 3, subunit E, a protein_coding Danio_rerio
ENSMUSG00000022336 Eif3e eukaryotic translation initiation factor 3, subunit E protein_coding Mus_musculus

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