C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, kainate 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000105737 GRIK5 9606 - 19:41998321-42069498 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262895 GRIK5-002 41998321-42065770 protein_coding
  ENST00000301218 GRIK5-001 42001786-42065805 protein_coding
  ENST00000454993 GRIK5-003 41998321-42042901 retained_intron
  ENST00000593562 GRIK5-004 41998814-42069498 protein_coding
  ENST00000594528 GRIK5-005 42021331-42065805 nonsense_mediated_decay
  ENST00000602210 GRIK5-006 41999243-42003764 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262895ENST00000301218ENST00000454993ENST00000593562ENST00000594528ENST00000602210
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262895 0.566±0.00 2.488±0.00 N/A 11.824±0.00 0.398±0.00 3.819±0.00 0.509±0.37 4.208±0.00 N/A 0.868±0.00 0.452±0.00 4.511±4.76 N/A 8.367±0.47
ENST00000301218 N/A N/A N/A N/A N/A 0.298±0.00 0.031±0.00 N/A N/A N/A N/A N/A N/A 12.578±0.00
ENST00000454993 N/A N/A N/A 1.457±0.00 0.073±0.00 2.968±0.00 N/A N/A 0.059±0.00 N/A N/A N/A N/A N/A
ENST00000593562 N/A N/A 1.432±0.00 1.714±0.00 0.100±0.06 N/A N/A N/A 0.675±0.00 0.023±0.00 N/A 0.117±0.00 N/A 2.359±0.00
ENST00000594528 N/A N/A N/A N/A N/A N/A N/A N/A 0.172±0.00 0.272±0.00 0.034±0.00 N/A 0.030±0.00 N/A
ENST00000602210 N/A N/A N/A N/A 0.734±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003YN CIL_0003YN_0001 CGP 19:41966582-42069498
CIL_0003XZ CIL_0003XZ_0001 CGP 19:41998321-42081565

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004970 IEA ionotropic glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IEA protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0006621 IEA protein retention in ER lumen
GO:0007165 IEA signal transduction
GO:0007268 TAS synaptic transmission
GO:0008066 IEA glutamate receptor activity
GO:0008328 IEA ionotropic glutamate receptor complex
GO:0014069 IEA postsynaptic density
GO:0015277 IDA kainate selective glutamate receptor activity
GO:0016020 IEA membrane
GO:0017124 IEA SH3 domain binding
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IBA dendrite
GO:0031630 IEA regulation of synaptic vesicle fusion to presynaptic membrane
GO:0032983 IBA kainate selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IEA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042391 IEA regulation of membrane potential
GO:0042734 IBA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043195 IEA terminal bouton
GO:0043204 IEA perikaryon
GO:0043525 IEA positive regulation of neuron apoptotic process
GO:0045211 IBA postsynaptic membrane
GO:0051649 IEA establishment of localization in cell
GO:0060079 IEA regulation of excitatory postsynaptic membrane potential
GO:0071333 IEA cellular response to glucose stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075764 grik5 glutamate receptor, ionotropic, kainate 5 protein_coding Danio_rerio
ENSDARG00000078151 GRIK5 (2 of 2) glutamate receptor, ionotropic, kainate 5 protein_coding Danio_rerio
ENSMUSG00000003378 Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) protein_coding Mus_musculus

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