C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000106852 LHX6 9606 - 9:122202577-122229626 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340587 LHX6-006 122202579-122228941 protein_coding
  ENST00000373754 LHX6-003 122202579-122227586 protein_coding
  ENST00000373755 LHX6-002 122202577-122227586 protein_coding
  ENST00000394319 LHX6-001 122202579-122228845 protein_coding
  ENST00000464484 LHX6-005 122204432-122213922 protein_coding
  ENST00000482062 LHX6-004 122204255-122213893 protein_coding
  ENST00000541397 LHX6-009 122202931-122228428 protein_coding
  ENST00000558672 LHX6-007 122217083-122226761 retained_intron
  ENST00000559529 LHX6-010 122227416-122229626 processed_transcript
  ENST00000559895 LHX6-008 122202583-122221740 protein_coding
  ENST00000560152 LHX6-012 122217105-122227123 retained_intron
  ENST00000560485 LHX6-011 122226999-122228431 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340587ENST00000373754ENST00000373755ENST00000394319ENST00000541397ENST00000559895ENST00000560152
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340587 1.931±0.00 0.638±0.00 N/A 0.795±0.00 0.839±0.00 N/A 0.240±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000373754 N/A N/A 0.038±0.00 1.449±0.00 N/A N/A 0.174±0.00 0.528±0.00 0.049±0.00 N/A 0.655±0.00 0.718±0.00 0.343±0.00 N/A
ENST00000373755 N/A N/A N/A 1.258±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000394319 4.556±0.00 1.778±0.00 N/A N/A 0.501±0.00 2.448±0.00 1.053±0.00 N/A N/A N/A 0.080±0.00 0.952±0.24 N/A 0.998±0.00
ENST00000541397 4.050±0.00 2.522±0.00 N/A 0.846±0.00 1.057±0.00 1.716±1.65 0.217±0.00 0.306±0.00 N/A 0.103±0.00 0.118±0.00 0.314±0.03 0.448±0.12 1.332±0.35
ENST00000559895 N/A N/A N/A N/A N/A N/A 0.165±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000560152 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.248±0.00 0.244±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006N7 CIL_0006N7_0001 CGP 9:122159908-122229626
CIL_0006N8 CIL_0006N8_0001 CGP 9:122202577-122264839

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0021799 ISS cerebral cortex radially oriented cell migration
GO:0021800 ISS cerebral cortex tangential migration
GO:0021853 ISS cerebral cortex GABAergic interneuron migration
GO:0021877 IEA forebrain neuron fate commitment
GO:0021884 IEA forebrain neuron development
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0048469 ISS cell maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006896 lhx6 LIM homeobox 6 protein_coding Danio_rerio
ENSMUSG00000026890 Lhx6 LIM homeobox protein 6 protein_coding Mus_musculus

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