C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox protein 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026890 Lhx6 10090 - 2:36081953-36105408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000112960 Lhx6-003 36081953-36105271 protein_coding
  ENSMUST00000112961 Lhx6-001 36081953-36104060 protein_coding
  ENSMUST00000112963 Lhx6-201 36081954-36105408 protein_coding
  ENSMUST00000112966 Lhx6-002 36081953-36104060 protein_coding
  ENSMUST00000112967 Lhx6-007 36081953-36105408 protein_coding
  ENSMUST00000136821 Lhx6-008 36083684-36094273 protein_coding
  ENSMUST00000137436 Lhx6-004 36101323-36105255 processed_transcript
  ENSMUST00000148852 Lhx6-006 36083687-36104891 protein_coding
  ENSMUST00000187180 Lhx6-005 36094225-36103592 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112960ENSMUST00000112961ENSMUST00000112963ENSMUST00000112966ENSMUST00000112967ENSMUST00000136821ENSMUST00000137436ENSMUST00000148852
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112960 1.312±0.43 0.336±0.14 0.189±0.00 1.664±0.55 0.754±0.26 0.214±0.09 0.389±0.05 0.180±0.08 0.178±0.13 N/A N/A 0.434±0.14 0.741±0.20 N/A
ENSMUST00000112961 N/A N/A N/A 1.776±0.13 N/A 0.088±0.00 N/A 0.147±0.05 0.125±0.01 0.183±0.09 N/A 0.269±0.09 0.903±0.00 0.586±0.00
ENSMUST00000112963 0.282±0.00 0.300±0.04 N/A N/A 0.660±0.38 N/A N/A N/A N/A 0.332±0.17 N/A 0.350±0.09 N/A 0.138±0.00
ENSMUST00000112966 1.266±0.00 N/A N/A 2.308±0.93 0.277±0.03 0.135±0.02 0.322±0.16 0.127±0.08 0.102±0.04 N/A 0.465±0.00 0.327±0.13 1.445±1.06 0.179±0.00
ENSMUST00000112967 0.594±0.21 0.281±0.17 0.143±0.00 N/A 0.246±0.06 0.198±0.14 0.376±0.12 N/A 0.143±0.08 0.240±0.00 N/A 0.366±0.09 0.291±0.00 N/A
ENSMUST00000136821 N/A 0.752±0.29 N/A N/A 1.023±0.15 N/A N/A 0.304±0.10 0.359±0.19 0.575±0.02 0.506±0.00 0.630±0.18 N/A 1.028±0.25
ENSMUST00000137436 N/A N/A N/A N/A N/A 0.041±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000148852 0.525±0.00 0.253±0.00 N/A N/A N/A N/A N/A N/A N/A 0.207±0.00 N/A 0.487±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006N7 CIL_0006N7_0002 CGP 2:36049458-36105408
CIL_0006N8 CIL_0006N8_0002 CGP 2:36081953-36136773

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0021799 IMP cerebral cortex radially oriented cell migration
GO:0021800 IMP cerebral cortex tangential migration
GO:0021853 IMP cerebral cortex GABAergic interneuron migration
GO:0021877 IGI forebrain neuron fate commitment
GO:0021884 IGI forebrain neuron development
GO:0021895 IGI cerebral cortex neuron differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0048469 IMP cell maturation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006896 lhx6 LIM homeobox 6 protein_coding Danio_rerio
ENSG00000106852 LHX6 LIM homeobox 6 protein_coding Homo_sapiens

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