C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 8 (androgen-induced)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000107831 FGF8 9606 - 10:101770130-101780369 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320185 FGF8-002 101770324-101775959 protein_coding
  ENST00000344255 FGF8-004 101770324-101775900 protein_coding
  ENST00000346714 FGF8-003 101770324-101775974 protein_coding
  ENST00000347978 FGF8-001 101770324-101776070 protein_coding
  ENST00000469792 FGF8-006 101770142-101776097 nonsense_mediated_decay
  ENST00000485728 FGF8-005 101770324-101775900 processed_transcript
  ENST00000618991 FGF8-201 101770130-101780369 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastHeartKidneyOvaryPlacentaTestisENST00000344255ENST00000346714ENST00000485728ENST00000618991
Transcript ID Brain Breast Heart Kidney Ovary Placenta Testis
ENST00000344255 N/A 0.275±0.00 N/A N/A N/A N/A N/A
ENST00000346714 0.332±0.00 N/A N/A 0.063±0.00 0.406±0.00 N/A 0.201±0.00
ENST00000485728 0.650±0.00 N/A 0.102±0.00 N/A 0.107±0.00 0.238±0.00 N/A
ENST00000618991 0.140±0.00 0.056±0.00 N/A N/A N/A N/A 0.723±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089J CIL_00089J_0001 VISTA 10:101185253-101786853
CIL_000942 CIL_000942_0001 VISTA 10:101206892-101808215
CIL_00099F CIL_00099F_0001 VISTA 10:101467436-102068636
CIL_00099E CIL_00099E_0001 VISTA 10:101480423-102081273
CIL_0005N9 CIL_0005N9_0001 CGP 10:101610664-101780369
CIL_0005NC CIL_0005NC_0001 CGP 10:101770130-101783413

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0001569 IEA patterning of blood vessels
GO:0001656 IEP metanephros development
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001759 IEA organ induction
GO:0001822 IEA kidney development
GO:0001823 IEP mesonephros development
GO:0001839 IEA neural plate morphogenesis
GO:0001947 IEA heart looping
GO:0001974 IEA blood vessel remodeling
GO:0003007 IEA heart morphogenesis
GO:0003148 ISS outflow tract septum morphogenesis
GO:0003151 IEA outflow tract morphogenesis
GO:0003198 ISS epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005105 IDA type 1 fibroblast growth factor receptor binding
GO:0005111 IDA type 2 fibroblast growth factor receptor binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0006915 IEA apoptotic process
GO:0006979 IEA response to oxidative stress
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007368 IEA determination of left/right symmetry
GO:0007369 NAS gastrulation
GO:0007507 IEA heart development
GO:0008045 IEA motor neuron axon guidance
GO:0008078 IEA mesodermal cell migration
GO:0008083 IEA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0008286 TAS insulin receptor signaling pathway
GO:0008406 IMP gonad development
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0009653 NAS anatomical structure morphogenesis
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0009897 IEA external side of plasma membrane
GO:0010628 IEA positive regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0021537 IEA telencephalon development
GO:0021543 IEA pallium development
GO:0021544 IEA subpallium development
GO:0021798 IEA forebrain dorsal/ventral pattern formation
GO:0021846 IEA cell proliferation in forebrain
GO:0021884 IEA forebrain neuron development
GO:0021954 IEA central nervous system neuron development
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030324 IEA lung development
GO:0030509 IEA BMP signaling pathway
GO:0030539 IEA male genitalia development
GO:0030878 IEA thyroid gland development
GO:0030916 IEA otic vesicle formation
GO:0030917 IEA midbrain-hindbrain boundary development
GO:0033563 IEA dorsal/ventral axon guidance
GO:0035050 IEA embryonic heart tube development
GO:0035108 IEA limb morphogenesis
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0035909 IEA aorta morphogenesis
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042056 IEA chemoattractant activity
GO:0042472 IEA inner ear morphogenesis
GO:0042476 IEP odontogenesis
GO:0042487 IEA regulation of odontogenesis of dentin-containing tooth
GO:0042493 IEA response to drug
GO:0043066 IEA negative regulation of apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0045165 IEA cell fate commitment
GO:0045840 IEA positive regulation of mitosis
GO:0046622 IEA positive regulation of organ growth
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0048699 IEA generation of neurons
GO:0048853 IEA forebrain morphogenesis
GO:0050918 IEA positive chemotaxis
GO:0051781 IEA positive regulation of cell division
GO:0055026 IMP negative regulation of cardiac muscle tissue development
GO:0060037 IEA pharyngeal system development
GO:0060070 IEA canonical Wnt signaling pathway
GO:0060128 IEA corticotropin hormone secreting cell differentiation
GO:0060129 IEA thyroid-stimulating hormone-secreting cell differentiation
GO:0060348 IMP bone development
GO:0060425 IEA lung morphogenesis
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0060563 IDA neuroepithelial cell differentiation
GO:0071542 IDA dopaminergic neuron differentiation
GO:0090134 IEA cell migration involved in mesendoderm migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000025219 Fgf8 fibroblast growth factor 8 protein_coding Mus_musculus

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