C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025219 Fgf8 10090 - 19:45736798-45742915 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026240 Fgf8-001 45736798-45742874 protein_coding
  ENSMUST00000026241 Fgf8-004 45736818-45742873 protein_coding
  ENSMUST00000111924 Fgf8-005 45736971-45742684 protein_coding
  ENSMUST00000111925 Fgf8-006 45736990-45742684 protein_coding
  ENSMUST00000111927 Fgf8-003 45736936-45742858 protein_coding
  ENSMUST00000111928 Fgf8-002 45736813-45742915 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainHeartKidneyLiverOvaryPlacentaTestisENSMUST00000026240ENSMUST00000026241ENSMUST00000111924ENSMUST00000111925ENSMUST00000111927ENSMUST00000111928
Transcript ID Adrenal Bladder Brain Heart Kidney Liver Ovary Placenta Testis
ENSMUST00000026240 N/A 0.009±0.00 0.047±0.00 N/A N/A N/A 0.478±0.10 N/A 0.166±0.00
ENSMUST00000026241 0.062±0.00 N/A 0.063±0.00 N/A N/A 0.014±0.00 N/A N/A 0.262±0.14
ENSMUST00000111924 N/A N/A 0.174±0.00 N/A N/A 0.050±0.02 1.050±0.50 0.066±0.02 0.372±0.08
ENSMUST00000111925 N/A N/A 0.168±0.01 N/A N/A N/A 0.832±0.29 N/A 0.211±0.03
ENSMUST00000111927 N/A N/A 0.128±0.03 N/A 0.039±0.00 N/A 0.479±0.22 N/A 0.175±0.04
ENSMUST00000111928 N/A N/A 0.215±0.13 0.029±0.00 N/A 0.019±0.00 0.755±0.26 0.055±0.00 0.283±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089J CIL_00089J_0002 VISTA 19:45175437-45776961
CIL_000942 CIL_000942_0002 VISTA 19:45193585-45794869
CIL_00099F CIL_00099F_0002 VISTA 19:45434459-46035623
CIL_00099E CIL_00099E_0002 VISTA 19:45446900-46047683
CIL_0005N9 CIL_0005N9_0002 CGP 19:45578254-45742915
CIL_0005NC CIL_0005NC_0002 CGP 19:45736798-45749591

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0001569 IGI patterning of blood vessels
GO:0001656 IEA metanephros development
GO:0001658 IMP branching involved in ureteric bud morphogenesis
GO:0001759 IGI organ induction
GO:0001822 IMP kidney development
GO:0001823 IEA mesonephros development
GO:0001839 IMP neural plate morphogenesis
GO:0001947 IMP heart looping
GO:0001974 IGI blood vessel remodeling
GO:0003007 IMP heart morphogenesis
GO:0003148 IGI outflow tract septum morphogenesis
GO:0003151 IGI outflow tract morphogenesis
GO:0003198 IDA epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0005104 IEA fibroblast growth factor receptor binding
GO:0005105 IEA type 1 fibroblast growth factor receptor binding
GO:0005111 IEA type 2 fibroblast growth factor receptor binding
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006915 IMP apoptotic process
GO:0006979 IEA response to oxidative stress
GO:0007368 IMP determination of left/right symmetry
GO:0007507 IMP heart development
GO:0008045 IEA motor neuron axon guidance
GO:0008078 IMP mesodermal cell migration
GO:0008083 IEA growth factor activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0008406 IEA gonad development
GO:0008543 IDA fibroblast growth factor receptor signaling pathway
GO:0009792 IMP embryo development ending in birth or egg hatching
GO:0009897 IEA external side of plasma membrane
GO:0010628 IMP positive regulation of gene expression
GO:0014070 IEA response to organic cyclic compound
GO:0021537 IMP telencephalon development
GO:0021543 IMP pallium development
GO:0021544 IMP subpallium development
GO:0021798 IMP forebrain dorsal/ventral pattern formation
GO:0021846 IMP cell proliferation in forebrain
GO:0021884 IEA forebrain neuron development
GO:0021954 IEA central nervous system neuron development
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030324 IMP lung development
GO:0030509 IDA BMP signaling pathway
GO:0030539 IDA male genitalia development
GO:0030878 IGI thyroid gland development
GO:0030916 IGI otic vesicle formation
GO:0030917 IMP midbrain-hindbrain boundary development
GO:0033563 IEA dorsal/ventral axon guidance
GO:0035050 IMP embryonic heart tube development
GO:0035108 IGI limb morphogenesis
GO:0035116 IGI embryonic hindlimb morphogenesis
GO:0035909 IGI aorta morphogenesis
GO:0042056 IEA chemoattractant activity
GO:0042472 IGI inner ear morphogenesis
GO:0042476 IEA odontogenesis
GO:0042487 IGI regulation of odontogenesis of dentin-containing tooth
GO:0042493 IEA response to drug
GO:0043066 IGI negative regulation of apoptotic process
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045165 IGI cell fate commitment
GO:0045840 IDA positive regulation of mitosis
GO:0046622 IGI positive regulation of organ growth
GO:0048699 IMP generation of neurons
GO:0048853 IMP forebrain morphogenesis
GO:0050918 IEA positive chemotaxis
GO:0051781 IEA positive regulation of cell division
GO:0055026 IEA negative regulation of cardiac muscle tissue development
GO:0060037 IGI pharyngeal system development
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060128 IDA corticotropin hormone secreting cell differentiation
GO:0060129 IDA thyroid-stimulating hormone-secreting cell differentiation
GO:0060348 IEA bone development
GO:0060425 IMP lung morphogenesis
GO:0060445 IGI branching involved in salivary gland morphogenesis
GO:0060563 IEA neuroepithelial cell differentiation
GO:0071542 IEA dopaminergic neuron differentiation
GO:0090134 IMP cell migration involved in mesendoderm migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107831 FGF8 fibroblast growth factor 8 (androgen-induced) protein_coding Homo_sapiens

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