C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine-rich, glioma inactivated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108231 LGI1 9606 + 10:93757885-93798159 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371413 LGI1-002 93757921-93798157 protein_coding
  ENST00000371418 LGI1-001 93757885-93798159 protein_coding
  ENST00000464250 LGI1-004 93777557-93778987 processed_transcript
  ENST00000478763 LGI1-003 93757921-93758912 processed_transcript
  ENST00000485458 LGI1-005 93777177-93777618 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371413ENST00000371418ENST00000478763
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371413 N/A 0.114±0.00 5.163±0.82 0.081±0.04 0.098±0.00 N/A N/A N/A 0.400±0.00 0.170±0.00 0.057±0.00 0.025±0.00 0.115±0.00
ENST00000371418 0.084±0.00 0.081±0.00 6.371±1.49 0.157±0.00 0.943±0.85 0.033±0.00 0.058±0.00 0.167±0.10 N/A 0.206±0.00 0.017±0.00 N/A 0.407±0.29
ENST00000478763 N/A N/A N/A 0.077±0.00 0.563±0.00 0.057±0.00 N/A 0.092±0.00 N/A 0.603±0.30 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000104 CIL_000104_0001 CGP 10:93667883-93798159
CIL_00067L CIL_00067L_0001 CGP 10:93757885-93956062

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IPI receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005615 IDA extracellular space
GO:0007399 TAS nervous system development
GO:0007411 IMP axon guidance
GO:0008283 TAS cell proliferation
GO:0030054 IEA cell junction
GO:0030307 IMP positive regulation of cell growth
GO:0031175 IMP neuron projection development
GO:0045202 IEA synapse
GO:0050806 ISS positive regulation of synaptic transmission
GO:0051260 IEA protein homooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020493 lgi1a leucine-rich, glioma inactivated 1a protein_coding Danio_rerio
ENSDARG00000058421 lgi1b leucine-rich, glioma inactivated 1b protein_coding Danio_rerio
ENSMUSG00000067242 Lgi1 leucine-rich repeat LGI family, member 1 protein_coding Mus_musculus

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