C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine-rich repeat LGI family, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000067242 Lgi1 10090 + 19:38264782-38308939 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000087252 Lgi1-001 38264782-38308939 protein_coding
  ENSMUST00000130039 Lgi1-003 38265410-38301269 protein_coding
  ENSMUST00000134832 Lgi1-002 38264782-38269046 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087252ENSMUST00000130039ENSMUST00000134832
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087252 0.356±0.06 0.177±0.08 0.470±0.02 5.235±3.00 0.074±0.04 0.102±0.04 1.336±0.39 0.056±0.02 0.025±0.03 0.132±0.07 1.009±0.55 0.204±0.11 0.014±0.01 0.067±0.03
ENSMUST00000130039 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.009±0.00 N/A
ENSMUST00000134832 N/A N/A N/A N/A N/A 0.034±0.00 N/A N/A N/A N/A N/A 0.094±0.03 0.005±0.00 0.093±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000104 CIL_000104_0002 CGP 19:38188481-38308939
CIL_00067L CIL_00067L_0002 CGP 19:38264782-38405607

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005615 ISS extracellular space
GO:0007411 IEA axon guidance
GO:0030054 IEA cell junction
GO:0030307 IEA positive regulation of cell growth
GO:0031175 IEA neuron projection development
GO:0045202 IEA synapse
GO:0050806 ISS positive regulation of synaptic transmission
GO:0051260 IEA protein homooligomerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020493 lgi1a leucine-rich, glioma inactivated 1a protein_coding Danio_rerio
ENSDARG00000058421 lgi1b leucine-rich, glioma inactivated 1b protein_coding Danio_rerio
ENSG00000108231 LGI1 leucine-rich, glioma inactivated 1 protein_coding Homo_sapiens

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