C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase interacting ArfGAP 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108262 GIT1 9606 - 17:29573469-29594054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000225394 GIT1-001 29573469-29589627 protein_coding
  ENST00000335356 GIT1-011 29582083-29589596 protein_coding
  ENST00000394869 GIT1-003 29573475-29589549 protein_coding
  ENST00000473217 GIT1-002 29573475-29579330 retained_intron
  ENST00000491377 GIT1-004 29575815-29576971 retained_intron
  ENST00000577466 GIT1-012 29582760-29583872 protein_coding
  ENST00000578266 GIT1-017 29574986-29576131 protein_coding
  ENST00000578670 GIT1-018 29574513-29576434 nonsense_mediated_decay
  ENST00000579536 GIT1-013 29581047-29582902 retained_intron
  ENST00000579937 GIT1-006 29574451-29589592 protein_coding
  ENST00000581348 GIT1-008 29574172-29589431 protein_coding
  ENST00000581925 GIT1-014 29576888-29581479 retained_intron
  ENST00000583413 GIT1-015 29582065-29594054 protein_coding
  ENST00000585148 GIT1-016 29576380-29581381 protein_coding
  ENST00000586574 GIT1-019 29576888-29581472 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225394ENST00000394869ENST00000473217ENST00000578670ENST00000579937ENST00000581348ENST00000581925ENST00000583413ENST00000585148ENST00000586574
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225394 30.115±0.00 9.201±0.00 N/A 16.109±0.00 12.154±0.00 6.335±5.80 10.760±0.00 7.611±0.00 0.948±0.59 19.562±18.77 13.983±0.00 9.119±8.50 14.044±7.93 61.992±5.57
ENST00000394869 N/A 5.037±0.00 N/A 15.938±13.30 N/A N/A N/A 3.991±0.00 N/A N/A 4.972±0.00 N/A N/A N/A
ENST00000473217 N/A 3.605±0.00 0.325±0.00 N/A N/A N/A N/A 0.298±0.00 N/A N/A N/A N/A N/A N/A
ENST00000578670 N/A N/A N/A N/A 10.475±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000579937 N/A N/A N/A 3.566±0.00 2.566±0.00 1.043±0.00 1.156±0.00 0.757±0.00 N/A 2.424±0.00 N/A N/A N/A N/A
ENST00000581348 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.946±0.00 N/A 26.656±0.00
ENST00000581925 N/A N/A N/A N/A 4.381±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000583413 N/A N/A N/A N/A N/A N/A N/A N/A 3.087±0.00 N/A N/A N/A N/A N/A
ENST00000585148 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.367±0.00 N/A N/A N/A
ENST00000586574 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.349±0.00 2.319±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009BZ CIL_0009BZ_0001 VISTA 17:29367684-29969856
CIL_000873 CIL_000873_0001 VISTA 17:29367702-29969870
CIL_0004GJ CIL_0004GJ_0002 CGP 17:29573469-29614761

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005925 IDA focal adhesion
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0008277 TAS regulation of G-protein coupled receptor protein signaling pathway
GO:0016020 IDA membrane
GO:0016235 IDA aggresome
GO:0032312 IEA regulation of ARF GTPase activity
GO:0043547 IEA positive regulation of GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039489 git1 G protein-coupled receptor kinase-interactor 1 protein_coding Danio_rerio
ENSMUSG00000011877 Git1 G protein-coupled receptor kinase-interactor 1 protein_coding Mus_musculus

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