C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E74-like factor 2 (ets domain transcription factor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109381 ELF2 9606 - 4:139028112-139177218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358635 ELF2-002 139057855-139084496 protein_coding
  ENST00000379549 ELF2-201 139057717-139084414 protein_coding
  ENST00000379550 ELF2-202 139057717-139139476 protein_coding
  ENST00000394235 ELF2-001 139057220-139177218 protein_coding
  ENST00000420916 ELF2-009 139060479-139084337 protein_coding
  ENST00000504314 ELF2-010 139061937-139072220 retained_intron
  ENST00000510408 ELF2-006 139058719-139084325 protein_coding
  ENST00000511006 ELF2-003 139136771-139177218 retained_intron
  ENST00000511184 ELF2-004 139101591-139177199 nonsense_mediated_decay
  ENST00000512627 ELF2-008 139060601-139084224 protein_coding
  ENST00000514577 ELF2-011 139061867-139073719 retained_intron
  ENST00000514606 ELF2-005 139066010-139084338 retained_intron
  ENST00000515489 ELF2-013 139028112-139060595 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358635ENST00000379549ENST00000379550ENST00000394235ENST00000510408ENST00000511184ENST00000512627ENST00000514577
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358635 2.322±0.00 5.414±0.00 N/A 1.480±0.00 3.849±0.00 3.180±0.00 2.222±0.00 1.876±0.00 1.261±0.00 3.868±0.00 2.227±0.00 4.366±2.08 2.671±0.31 5.111±0.00
ENST00000379549 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.121±0.00 N/A N/A
ENST00000379550 2.908±0.00 1.529±0.00 1.797±0.00 2.269±0.57 2.779±1.71 2.560±0.52 1.649±0.14 2.889±0.99 5.053±4.58 5.803±0.74 2.239±0.04 2.503±0.63 3.386±2.27 15.100±9.79
ENST00000394235 1.007±0.00 N/A 1.542±0.00 N/A 1.389±0.00 N/A 0.456±0.00 0.722±0.00 0.252±0.00 2.908±0.00 N/A 1.122±0.07 N/A N/A
ENST00000510408 4.496±0.00 6.562±0.00 N/A 2.150±0.00 3.477±0.00 2.807±0.00 1.398±0.51 2.771±0.00 N/A N/A 1.283±0.00 3.038±0.38 2.972±0.34 6.366±0.00
ENST00000511184 N/A N/A 1.810±0.00 N/A 2.916±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000512627 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.857±0.00
ENST00000514577 N/A N/A N/A N/A N/A N/A 2.897±0.00 5.163±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001Q CIL_00001Q_0001 CGP 4:138164097-139045752
CIL_0006YJ CIL_0006YJ_0002 CGP 4:139015789-139177218
CIL_00001P CIL_00001P_0001 CGP 4:139028112-139280338

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0030154 IBA cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019459 elf2a E74-like factor 2a (ets domain transcription factor) protein_coding Danio_rerio
ENSMUSG00000037174 Elf2 E74-like factor 2 protein_coding Mus_musculus

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