C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chloride channel, voltage-sensitive 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109572 CLCN3 9606 + 4:169612633-169723673 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000347613 CLCN3-002 169620526-169720545 protein_coding
  ENST00000360642 CLCN3-004 169620529-169720278 protein_coding
  ENST00000502998 CLCN3-010 169680068-169680731 processed_transcript
  ENST00000504131 CLCN3-201 169662722-169723183 protein_coding
  ENST00000506924 CLCN3-008 169635983-169643168 processed_transcript
  ENST00000507875 CLCN3-005 169660062-169713187 protein_coding
  ENST00000511092 CLCN3-006 169612633-169689145 protein_coding
  ENST00000512813 CLCN3-007 169620552-169687755 protein_coding
  ENST00000513761 CLCN3-001 169620521-169723673 protein_coding
  ENST00000515420 CLCN3-009 169695631-169706888 protein_coding
  ENST00000613795 CLCN3-202 169660062-169723187 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000347613ENST00000360642ENST00000504131ENST00000507875ENST00000511092ENST00000513761ENST00000613795
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000347613 1.679±0.00 N/A 2.251±0.00 7.517±0.00 1.941±0.00 1.589±0.00 2.857±0.00 2.757±1.20 N/A N/A 3.241±0.00 3.062±0.80 2.077±0.72 N/A
ENST00000360642 N/A N/A 2.114±0.00 5.913±0.00 2.876±0.00 N/A 4.110±0.00 2.050±0.00 6.384±0.00 5.542±0.00 1.588±0.00 3.386±0.00 1.434±0.00 N/A
ENST00000504131 1.148±0.00 N/A 1.996±0.00 5.531±0.00 3.232±0.00 1.615±0.00 2.918±0.00 4.932±1.42 1.649±0.00 4.687±0.00 1.083±0.00 2.228±0.51 2.270±0.54 3.160±0.00
ENST00000507875 N/A N/A N/A 6.603±0.00 N/A 5.767±0.00 3.431±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000511092 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.851±0.00 N/A
ENST00000513761 N/A 0.459±0.00 N/A N/A N/A 0.921±0.00 N/A N/A N/A 0.916±0.00 0.701±0.00 2.233±1.25 N/A N/A
ENST00000613795 N/A N/A 1.718±0.00 16.574±0.00 3.776±0.00 6.046±0.00 3.802±0.90 N/A 4.501±0.00 N/A N/A 2.359±1.95 0.905±0.00 3.771±2.14

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005244 IEA voltage-gated ion channel activity
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005254 TAS chloride channel activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006810 TAS transport
GO:0006811 IEA ion transport
GO:0006821 IEA chloride transport
GO:0006885 TAS regulation of pH
GO:0009986 NAS cell surface
GO:0012506 IDA vesicle membrane
GO:0015297 IEA antiporter activity
GO:0016020 IDA:IEA membrane
GO:0016021 TAS integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0030165 IDA PDZ domain binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031410 IEA cytoplasmic vesicle
GO:0034220 TAS ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042803 NAS protein homodimerization activity
GO:0044070 IEA regulation of anion transport
GO:0046982 IDA protein heterodimerization activity
GO:0048388 TAS endosomal lumen acidification
GO:0055085 TAS:IEA transmembrane transport
GO:1902476 TAS chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003269 clcn3 chloride channel 3 protein_coding Danio_rerio
ENSMUSG00000004319 Clcn3 chloride channel 3 protein_coding Mus_musculus

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