C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chloride channel 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004319 Clcn3 10090 - 8:60910389-60983300 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004430 Clcn3-002 60911923-60983239 protein_coding
  ENSMUST00000056508 Clcn3-003 60910389-60955233 protein_coding
  ENSMUST00000093490 Clcn3-001 60910389-60983300 protein_coding
  ENSMUST00000110301 Clcn3-004 60911923-60983239 protein_coding
  ENSMUST00000110302 Clcn3-006 60911896-60954748 protein_coding
  ENSMUST00000129672 Clcn3-010 60911923-60955233 retained_intron
  ENSMUST00000132234 Clcn3-009 60928295-60954779 retained_intron
  ENSMUST00000145493 Clcn3-007 60938640-60983286 retained_intron
  ENSMUST00000145741 Clcn3-005 60910861-60922960 processed_transcript
  ENSMUST00000147824 Clcn3-008 60935357-60983244 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004430ENSMUST00000056508ENSMUST00000093490ENSMUST00000110301ENSMUST00000110302ENSMUST00000145493ENSMUST00000145741
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004430 1.452±0.46 2.567±0.00 N/A N/A 2.419±0.51 2.538±0.42 N/A 3.744±1.55 2.633±0.74 N/A N/A 2.986±1.35 2.812±0.00 2.061±0.16
ENSMUST00000056508 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.956±0.00 N/A N/A N/A
ENSMUST00000093490 2.636±0.43 6.483±2.31 6.564±2.01 13.805±2.26 4.019±1.26 7.120±0.81 3.331±1.05 10.604±1.74 9.780±6.18 6.466±0.69 4.740±0.48 4.218±2.80 6.589±4.48 2.235±0.29
ENSMUST00000110301 2.219±1.20 4.045±0.67 N/A N/A 2.213±0.84 5.669±1.46 1.811±0.25 4.808±1.66 2.831±0.80 3.516±0.91 N/A 3.590±1.52 3.452±0.32 4.422±1.90
ENSMUST00000110302 N/A N/A N/A N/A N/A N/A 1.282±0.08 N/A 1.797±0.00 N/A N/A N/A N/A 1.582±0.20
ENSMUST00000145493 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.154±0.00 N/A N/A
ENSMUST00000145741 N/A 4.426±0.00 N/A N/A 2.110±0.43 N/A 1.738±0.00 N/A 10.925±0.00 N/A N/A N/A 2.034±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005244 IEA voltage-gated ion channel activity
GO:0005247 IEA voltage-gated chloride channel activity
GO:0005254 IEA chloride channel activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0005769 IEA early endosome
GO:0005770 IEA late endosome
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006811 IEA ion transport
GO:0006821 IEA chloride transport
GO:0012506 IEA vesicle membrane
GO:0015297 IEA antiporter activity
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0030165 IEA PDZ domain binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031410 IEA cytoplasmic vesicle
GO:0031902 TAS late endosome membrane
GO:0034220 IEA ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0044070 IEA regulation of anion transport
GO:0046982 IEA protein heterodimerization activity
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003269 clcn3 chloride channel 3 protein_coding Danio_rerio
ENSG00000109572 CLCN3 chloride channel, voltage-sensitive 3 protein_coding Homo_sapiens

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