C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109618 SEPSECS 9606 - 4:25120014-25160442 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358971 SEPSECS-003 25122255-25160394 nonsense_mediated_decay
  ENST00000382103 SEPSECS-001 25120014-25160442 protein_coding
  ENST00000503150 SEPSECS-006 25124081-25156098 nonsense_mediated_decay
  ENST00000505513 SEPSECS-005 25127264-25155231 retained_intron
  ENST00000513285 SEPSECS-004 25158945-25160398 protein_coding
  ENST00000514585 SEPSECS-002 25123850-25160431 nonsense_mediated_decay
  ENST00000515272 SEPSECS-007 25125301-25127308 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358971ENST00000382103ENST00000514585
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358971 0.365±0.00 1.875±0.00 0.589±0.00 0.656±0.15 1.563±1.11 0.185±0.08 1.628±0.96 N/A 0.639±0.00 0.336±0.00 N/A N/A 1.115±0.00
ENST00000382103 1.058±0.00 N/A 0.612±0.00 0.442±0.03 0.530±0.04 0.180±0.01 1.876±1.00 1.270±0.64 0.337±0.19 0.103±0.00 0.909±0.16 0.711±0.03 1.153±0.32
ENST00000514585 N/A N/A N/A 1.886±0.00 N/A 0.609±0.00 N/A 1.580±0.00 1.727±0.00 0.277±0.00 1.797±0.77 2.383±0.00 3.896±2.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TJ CIL_0003TJ_0002 CGP 4:24998847-25160442
CIL_0002OX CIL_0002OX_0001 CGP 4:25120014-25279092

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000049 ISS tRNA binding
GO:0001514 ISS selenocysteine incorporation
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0008152 IEA metabolic process
GO:0016740 IEA transferase activity
GO:0016785 IEA transferase activity, transferring selenium-containing groups
GO:0030170 IEA pyridoxal phosphate binding
GO:0097056 IEA selenocysteinyl-tRNA(Sec) biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033861 sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase protein_coding Danio_rerio
ENSMUSG00000029173 Sepsecs Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase protein_coding Mus_musculus

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