C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nei endonuclease VIII-like 3 (E. coli)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000109674 NEIL3 9606 + 4:177309836-177362943 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264596 NEIL3-001 177309836-177362943 protein_coding
  ENST00000513321 NEIL3-002 177309903-177354279 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000264596ENST00000513321
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000264596 N/A N/A 0.195±0.19 0.298±0.27 0.013±0.00 0.019±0.00 0.075±0.00 N/A 0.078±0.04 0.245±0.09 1.007±0.24
ENST00000513321 0.202±0.00 0.073±0.03 0.064±0.00 0.073±0.00 0.052±0.03 0.061±0.00 0.046±0.00 0.223±0.00 0.080±0.06 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GU CIL_0000GU_0002 CGP 4:177309836-177442503

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000405 ISS bubble DNA binding
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003676 IEA nucleic acid binding
GO:0003684 IEA damaged DNA binding
GO:0003690 ISS double-stranded DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0003906 IDA:IEA DNA-(apurinic or apyrimidinic site) lyase activity
GO:0005634 IDA nucleus
GO:0006281 IEA DNA repair
GO:0006284 ISS:IEA base-excision repair
GO:0006289 IEA nucleotide-excision repair
GO:0008270 IEA zinc ion binding
GO:0016799 IEA hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0019104 ISS DNA N-glycosylase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020079 neil3 nei endonuclease VIII-like 3 (E. coli) protein_coding Danio_rerio
ENSMUSG00000039396 Neil3 nei like 3 (E. coli) protein_coding Mus_musculus

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