C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-box 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000112837 TBX18 9606 - 6:84687351-84764519 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330469 TBX18-007 84687351-84688747 retained_intron
  ENST00000369663 TBX18-001 84732602-84764519 protein_coding
  ENST00000606325 TBX18-003 84744261-84763453 protein_coding
  ENST00000606521 TBX18-004 84742024-84763448 processed_transcript
  ENST00000606621 TBX18-002 84760283-84763355 protein_coding
  ENST00000606784 TBX18-006 84687373-84763453 protein_coding
  ENST00000607343 TBX18-005 84741067-84741802 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000330469ENST00000369663ENST00000606325ENST00000606784ENST00000607343
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000330469 N/A N/A N/A N/A N/A N/A N/A N/A 0.981±0.00 N/A N/A N/A
ENST00000369663 1.451±0.00 1.052±0.00 0.107±0.05 0.856±0.51 0.592±0.00 0.474±0.00 0.556±0.54 0.203±0.00 0.076±0.00 0.506±0.18 0.314±0.05 0.663±0.36
ENST00000606325 N/A N/A 0.578±0.00 N/A N/A 0.662±0.00 0.075±0.00 N/A 0.962±0.47 N/A N/A N/A
ENST00000606784 N/A N/A 0.218±0.00 N/A N/A N/A N/A N/A N/A 0.066±0.00 N/A N/A
ENST00000607343 0.133±0.00 0.158±0.00 0.227±0.00 0.402±0.19 0.063±0.01 0.081±0.01 1.975±0.00 N/A N/A 0.130±0.08 N/A 0.034±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00066X CIL_00066X_0001 CGP 6:84124241-84764519
CIL_0007K0 CIL_0007K0_0001 UCNEbase 6:84361462-85614404
CIL_00066W CIL_00066W_0001 CGP 6:84687351-85495791

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0001106 ISS RNA polymerase II transcription corepressor activity
GO:0001756 IEA somitogenesis
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0003163 IEA sinoatrial node development
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA:ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007605 IEA sensory perception of sound
GO:0009948 IEA anterior/posterior axis specification
GO:0016331 IEA morphogenesis of embryonic epithelium
GO:0022409 IEA positive regulation of cell-cell adhesion
GO:0030154 IEA cell differentiation
GO:0042803 ISS protein homodimerization activity
GO:0046982 ISS protein heterodimerization activity
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051145 IEA smooth muscle cell differentiation
GO:0060829 ISS negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation
GO:0072189 IEA ureter development
GO:0090103 IEA cochlea morphogenesis
GO:2000729 IEA positive regulation of mesenchymal cell proliferation involved in ureter development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036930 tbx18 T-box 18 protein_coding Danio_rerio
ENSMUSG00000032419 Tbx18 T-box18 protein_coding Mus_musculus

Loading