C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114331 ACAP2 9606 - 3:195274736-195443078 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326793 ACAP2-001 195274736-195443078 protein_coding
  ENST00000423531 ACAP2-006 195333082-195356212 protein_coding
  ENST00000439666 ACAP2-005 195381009-195442855 protein_coding
  ENST00000439758 ACAP2-007 195302148-195342609 protein_coding
  ENST00000447662 ACAP2-004 195381026-195442905 nonsense_mediated_decay
  ENST00000450200 ACAP2-010 195292314-195301644 protein_coding
  ENST00000466876 ACAP2-011 195285328-195291745 retained_intron
  ENST00000471593 ACAP2-008 195326332-195336965 retained_intron
  ENST00000472860 ACAP2-012 195279034-195279799 processed_transcript
  ENST00000475905 ACAP2-009 195295446-195302115 retained_intron
  ENST00000480906 ACAP2-002 195335899-195443043 retained_intron
  ENST00000481463 ACAP2-013 195342606-195442276 processed_transcript
  ENST00000484296 ACAP2-014 195297224-195306865 retained_intron
  ENST00000490224 ACAP2-003 195441793-195443044 retained_intron
  ENST00000618471 ACAP2-201 195278515-195442907 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000326793ENST00000450200ENST00000480906ENST00000618471
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000326793 6.508±0.00 3.866±0.00 2.748±0.00 2.704±0.00 3.452±1.10 3.104±0.80 1.688±0.40 1.873±0.87 3.349±2.13 4.650±3.09 1.168±0.45 3.344±2.00 1.875±0.71 1.115±0.00
ENST00000450200 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.953±0.00
ENST00000480906 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.596±0.00 N/A N/A N/A
ENST00000618471 N/A N/A N/A 2.017±0.00 N/A 2.524±0.00 N/A N/A 3.960±0.00 3.966±0.00 N/A 2.119±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CC CIL_0006CC_0001 CGP 3:195068279-195443078
CIL_0003O6 CIL_0003O6_0002 CGP 3:195274736-195543386

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0010008 ISS endosome membrane
GO:0016020 IDA membrane
GO:0017137 IEA Rab GTPase binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0036010 ISS protein localization to endosome
GO:0043547 IEA positive regulation of GTPase activity
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056478 ACAP2 (1 of 2) ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Danio_rerio
ENSDARG00000060783 acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Danio_rerio
ENSMUSG00000049076 Acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Mus_musculus

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