C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049076 Acap2 10090 - 16:31092413-31201238 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000058033 Acap2-201 31092413-31201238 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058033
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058033 8.284±3.85 13.958±1.99 15.583±3.67 5.219±0.94 11.529±3.24 15.533±4.62 2.850±0.54 4.784±1.35 3.825±0.42 21.033±2.62 1.456±0.44 15.653±5.35 4.631±1.08 1.615±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CC CIL_0006CC_0002 CGP 16:30955627-31201238
CIL_0003O6 CIL_0003O6_0003 CGP 16:31092413-31275277

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0010008 ISS endosome membrane
GO:0016020 IEA membrane
GO:0017137 IPI Rab GTPase binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0036010 ISS protein localization to endosome
GO:0043547 IEA positive regulation of GTPase activity
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056478 ACAP2 (1 of 2) ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Danio_rerio
ENSDARG00000060783 acap2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Danio_rerio
ENSG00000114331 ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 protein_coding Homo_sapiens

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