C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin C type 1 (slow)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114854 TNNC1 9606 - 3:52451102-52454070 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000232975 TNNC1-001 52451102-52454070 protein_coding
  ENST00000461086 TNNC1-004 52451439-52451991 retained_intron
  ENST00000496590 TNNC1-002 52451415-52452834 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000232975ENST00000461086ENST00000496590
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000232975 0.851±0.00 2.000±0.00 0.873±0.00 0.270±0.00 45.922±42.76 0.896±0.43 1585.332±757.49 7.682±0.00 1.648±1.48 24.471±10.14 1848.449±922.71 2.328±1.36 15.990±9.48 37.685±33.99
ENST00000461086 N/A N/A 0.979±0.00 0.145±0.00 N/A N/A N/A N/A 1.393±1.32 N/A N/A N/A N/A N/A
ENST00000496590 N/A N/A N/A N/A N/A N/A N/A 0.092±0.00 N/A N/A N/A 1.884±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002086 IEA diaphragm contraction
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0005861 IDA troponin complex
GO:0006937 IDA regulation of muscle contraction
GO:0010038 IEA response to metal ion
GO:0015629 IDA actin cytoskeleton
GO:0030049 TAS muscle filament sliding
GO:0031013 IPI troponin I binding
GO:0031014 IPI troponin T binding
GO:0032972 ISS regulation of muscle filament sliding speed
GO:0042803 IDA protein homodimerization activity
GO:0043292 IEA contractile fiber
GO:0043462 ISS regulation of ATPase activity
GO:0048306 IPI calcium-dependent protein binding
GO:0051015 ISS actin filament binding
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011400 tnnc1a troponin C type 1a (slow) protein_coding Danio_rerio
ENSDARG00000037539 tnnc1b troponin C type 1b (slow) protein_coding Danio_rerio
ENSMUSG00000091898 Tnnc1 troponin C, cardiac/slow skeletal protein_coding Mus_musculus

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